Results 1 to 10 of about 276,679 (267)

Association of HScore Parameters with Severe COVID-19: A Systematic Review and Meta-Analysis [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Several reports have associated the severe Coronavirus disease-2019 (sCOVID-19) with secondary-hemophagocytic lymphohistiocytosis (sHLH) and proposed utilizing the hemophagocytic syndrome diagnostic score (HScore) for sCOVID-19 patients.
Mohammad Hossein Kazemi, Bentolhoda Kuhestani Dehaghi, Elham Roshandel, Hossein Bonakchi, Sayeh Parkhideh, Mahshid Mehdizadeh, Abbas Hajifathali   +6 more
doaj   +1 more source

Analysis of Correlation between Body Mass Index and the Incidence of Graft-Versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

Journal of Kerman University of Medical Sciences, 2021
Background: Graft-versus-host disease (GVHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Identifiying the probable risk factors can help the clinicians manage the consequences of GVHD.
Masoud Soleimani, Samira Mohammad Zadeh, Sina Salari, Maryam Salimi, Leila Noorazar, Mehdi Amini Neysiani, Abbas Hajifathali   +6 more
doaj   +1 more source

Donor and Recipient Individual Factors as Predictive Markers of Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation; Dream or Reality

Acta Medica Iranica, 2021
Low overall survival (OS) still is a major concern of allogeneic hematopoietic stem cell transplantation (allo-HSCT), which is affected by many individual and environmental factors. In this study, we retrospectively evaluated the association of donor and
Pooya Eslampour, Sayeh Parkhideh, Mahshid Mehdizadeh, Samira Karami, Elham Roshandel, Hossein Bonakchi, Abbas Hajifathali   +6 more
doaj   +1 more source

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

BMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong, Zhijie Kang, Dan Huang, Xuehong Zhang, Yuan Gao, Haina Wang, Weiling Li, Jinsong Yan   +7 more
doaj   +1 more source

Immunotherapy with adoptive cytomegalovirus‐specific T cells transfer: Summarizing latest gene engineering techniques

Health Science Reports, 2021
Cytomegalovirus (CMV) infection remains a major complication following allogeneic hematopoietic stem cell transplantation (HSCT). T cell response plays a critical role in inducing long‐term immunity against CMV infection/reactivation that impairs during ...
Mahshid Mehdizadeh, Samira Karami, Haniyeh Ghaffari Nazari, Ghazaleh Sankanian, Mohsen Hamidpour, Abbas Hajifathali   +5 more
doaj   +1 more source

Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution

Hematology, 2022
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino, Atsushi Jinguji, Tomoya Sato, Ayato Nakadate   +3 more
doaj   +1 more source

Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation:a Global Observational Study [PDF]

, 2013
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro, Horowitz, Mary, Passweg, Jakob, Bouzas, Luis Fernando, Szer, Jeff, Niederwieser, Dietger, Gratwohl, Alois, Aljurf, Mahmoud, Iida, Minako, Kodera, Yoshihisa, Worldwide Network Blood Marrow Tra, Pasquini, Marcelo C., Marrow Transplantation,, Lipton, Jeff, Worldwide Network of Blood,, Gratwohl, Michael, Baldomero, Helen, Frauendorfer, Karl   +17 more
core   +1 more source

Identification of the niche and phenotype of the first human hematopoietic stem cells [PDF]

, 2014
In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra ...
Stanislav Rybtsov, Anderson, Richard A., Turner, Marc L., Anderson, Richard A, Ivanovs, Andrejs, Andrejs Ivanovs, Richard A. Anderson, Turner, Marc L, Marc L. Turner, Alexander Medvinsky, Medvinsky, Alexander, Rybtsov, Stanislav   +11 more
core   +1 more source

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Glenda J. Dickson, Pamela M. Corrigan, Freeburn, R.W., Robin W. Freeburn, Dickson, Glenda, Thompson, Alexander, Ramsey, Joanne, Helen Wheadon, Wheadon, H., Dickson, G.J., Edwina Dobbin, Alexander Thompson, Ramsey, J.M., Corrigan, P.M., Joanne M. Ramsey, Dobbin, E., Thompson, A.   +16 more
core   +1 more source

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

Cancer Cell International, 2022
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li, Jinsong Yan   +10 more
doaj   +1 more source