Results 161 to 170 of about 1,311,555 (408)

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

An optimized peptide vaccine strategy capable of inducing multivalent CD8+ T cell responses with potent antitumor effects

OncoImmunology, 2015
Therapeutic cancer vaccines are an attractive alternative to conventional therapies for treating malignant tumors, and successful tumor eradication depends primarily on obtaining high numbers of long-lasting tumor-reactive CD8+ T cells.
Hyun-Il Cho, Soo-Hyun Jung, Hyun-Jung Sohn, Esteban Celis, Tai-Gyu Kim   +4 more
doaj   +1 more source

Long-term outcome after a treosulfan-based conditioning regimen for patients with acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation [PDF]

, 2017
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for patients with acute myeloid leukemia (AML). However, post-HCT relapse and regimen-related toxicity remain significant barriers to long-term survival.
Al Mumma, Baron, Boztug, Boztug, Bredeson, Burroughs, Carreras, Casper, Casper, Cieri, Copelan, Dalle, Danylesko, Fichtner, Galaup, Glowka, Gupta, Gyurkocza, Kroger, Kroger, Majhail, Meinhardt, Munkelt, Nagler, Nagler, Palmer, Pel, Richardson, Rizzo, Savani, Savani, Scheulen, Schmidmaier, Schmitt, Sengsayadeth, Sengsayadeth, Shimoni, Shimoni, Slatter, ten Brink, Wachowiak, Williams   +41 more
core   +1 more source

A Rare Case of Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplant Patient [PDF]

, 2015
Kamal Kant Sahu, Gaurav Prakash, Alka Khadwal, Subhash Varma, Pankaj Malhotra   +4 more
openalex   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

TREML2 enhances sensitivity of acute myeloid leukemia cells to chemotherapy by inhibiting the NF-κB/CXCL10 pathway

Blood Science
The triggering receptors expressed on myeloid cells (TREMs) family of cell surface receptors are mainly expressed by myeloid cells. The expression profile of TREM-like 2 (TREML2), a TREM family member, in patients with acute myeloid leukemia (AML) is ...
Xin Zhang, Shuheng Yan, Xuehong Zhang, Dan Huang, Jiayin Zhou, Xiaoting Song, Yuchao Hao, Xijia Wang, Jinsong Yan   +8 more
doaj   +1 more source

Persistence of Yellow Fever Immunization–Induced Antibodies in Allogeneic Hematopoietic Stem Cell Transplant Recipients [PDF]

, 2018
Marcel Adler, Valérie Lapierre, Riwa Sakr, Jean Bourhis, Bertrand Gachot, Cristina Castilla‐Llorente, Benjamin Wyplosz   +6 more
openalex   +1 more source

Incidence and Outcome of Secondary Graft Failure in Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia: A Single Center Study

, 2023
Jay A. Read, Katie Greenwood, Brian D. Friend, Tami John, Baheyeldin Salem, Erin Doherty, Khaled Yassine, A. T. George, Gabriela Llaurador, John P. Craddock, Saleh Bhar, Swati Naik, Alison A. Bertuch, Robert A. Krance, Caridad Martinez, Ghadir Sasa   +15 more
openalex   +1 more source

Gene-Modified HIV-Protected Hematopoietic Stem Cells [PDF]

, 2020
National Cancer Institute
openalex   +1 more source