Results 271 to 280 of about 1,311,555 (408)

The Critical Role of Fractionated Urine Glycosaminoglycans in the Evaluation of Mucopolysaccharidosis Type II in Four Unrelated Families

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Since 2015, Ann and Robert H. Lurie Children's Hospital has performed diagnostic testing for infants who screen positive for mucopolysaccharidosis type II (MPS II) on the Illinois newborn screen. Preliminary diagnostic testing includes measurement of plasma iduronate‐2‐sulfatase enzyme activity and urinary glycosaminoglycan analysis, followed ...
Carly A. Rasmussen, Monika Izdebski, Allison Paltzer, Rachel Hickey, Laura Pollard, Joshua Baker   +5 more
wiley   +1 more source

Donor selection for patients with HLA-homozygous haplotypes in allogeneic hematopoietic stem cell transplantation. [PDF]

Ann Hematol
Yoshinaga N, Iwasaki M, Kato K, Kimura F, Hirayama M, Kanaya M, Morishima S, Uchida N, Doki N, Fukuda T, Kanda Y, Nishida T, Hasegawa Y, Kako S, Tanaka M, Kurokawa M, Asada N, Kawakita T, Kataoka K, Kondo Y, Imada K, Ichinohe T, Onizuka M, Atsuta Y, Kanda J.   +24 more
europepmc   +1 more source

A Single SNP in ADRB2 Halves the Opioid Requirement for Mucositis Pain in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation

, 2018
M. Christa Krupski, Laura B. Ramsey, Norbert Weidner, Adam Lane, Stella M. Davies, Ashley Teusink‐Cross, Sharat Chandra, Kelly E. Lake, Kejian Zhang, Denise Bellman, Senthilkumar Sadhasivam, Parinda A. Mehta   +11 more
openalex   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Mineral disorders after hematopoietic stem cell transplantation in patients receiving parenteral nutrition. [PDF]

Hematol Transfus Cell Ther
Hortencio TDR, Salamonde JDF, Springer AMM, Vigorito AC, Mendonça VA, Nogueira RJN.   +5 more
europepmc   +1 more source

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.

Blood, 2014
Y. Taur, R. Jenq, M. Perales, E. Littmann, Sejal Morjaria, Lilan Ling, Daniel No, Asia Gobourne, A. Viale, P. Dahi, D. Ponce, J. Barker, S. Giralt, M. V. D. van den Brink, E. Pamer   +14 more
semanticscholar   +1 more source

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

The systemic costs of hematopoietic stem cell aging. [PDF]

Development
Puri G, Blanc RS.
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source