Results 291 to 300 of about 1,311,555 (408)

Regulation of hematopoietic stem cell by the bone marrow microenvironment "niche".

, 2004
Fumio Arai, Atsushi Hirao, Toshio Suda
openalex   +2 more sources

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Analysis of HLA genotype in the recipients' different tissues after haploidentical hematopoietic stem cell transplantation. [PDF]

Front Immunol
Liu J, Yang BN, Quan ZR, Zhang YM, Song JM, Deng ZH, Zou HY.   +6 more
europepmc   +1 more source

Cytarabine Monotherapy as Bridging Treatment for Hematopoietic Stem Cell Transplantation in Children with Juvenile Myelomonocytic Leukemia

, 2012
Woo Suck Suh, Mun Sung Cho, Jae Wook Lee, Pil Sang Jang, Nack Gyun Chung, Dae Chul Jeong, Bin Cho, Hack Ki Kim   +7 more
openalex   +1 more source

Clinical Practice Guideline for the Treatment of BK-Virus Induced Hemorrhagic Cystitis in the Post-Allogeneic Hematopoietic Stem Cell Transplant Setting

, 2012
Devi D Morrison, Thomas Samith Kochuparambil, David L. DeRemer, Vamsi Kota, Anand Jillella, Farrukh T. Awan   +5 more
openalex   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Next generation targeted non-genotoxic conditioning for hematopoietic stem cell and hematopoietic stem cell-based gene therapy. [PDF]

Front Immunol
Okalova J, Spencer TH, Chandrakasan S.
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Bnip3lb-driven mitophagy maintains fate of the embryonic hematopoietic stem cell pool. [PDF]

Nat Commun
Meader E, Walcheck MT, Leder MR, Delaney P, Falchetti M, Jing R, Li C, Kambli NK, Wrighton PJ, Sugden WW, Najia MA, Oderberg IM, Taylor VM, LeBlanc ZC, Quenzer ED, Lim SE, Schlaeger T, Daley GQ, Goessling W, North TE.   +19 more
europepmc   +1 more source

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.

Cell Stem Cell, 2015
S. Haas, Jenny Hansson, Daniel Klimmeck, D. Loeffler, Lars Velten, H. Uckelmann, Stephan Wurzer, Áine M. Prendergast, Alexandra Schnell, K. Hexel, Rachel Santarella-Mellwig, S. Blaszkiewicz, A. Kuck, H. Geiger, M. Milsom, L. Steinmetz, T. Schroeder, A. Trumpp, J. Krijgsveld, M. Essers   +19 more
semanticscholar   +1 more source