Results 361 to 370 of about 1,311,555 (408)
Some of the next articles are maybe not open access.
Cancer Investigation, 2002
In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
openaire +2 more sources
In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
openaire +2 more sources
Characterization of Hematopoietic Stem Cells
Annals of the New York Academy of Sciences, 1995On the basis of density-separated mononuclear cells isolated from bone marrow, peripheral blood, and cord blood, we have repeatedly shown good correlation between two-color flow cytometric (FACS) CD34 analysis and colony formation in the clonogenic assay.
G, Fritsch +7 more
openaire +2 more sources
Current Opinion in Immunology, 2014
Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
openaire +2 more sources
Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
openaire +2 more sources
Pediatrics, 2004
The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
openaire +2 more sources
The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
openaire +2 more sources
Birth Defects Research Part C: Embryo Today: Reviews, 2003
AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
openaire +2 more sources
AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
openaire +2 more sources
2013
Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
openaire +1 more source
Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
openaire +1 more source
Mobilization of hematopoietic stem cells
Blood Reviews, 2000Hematopoietic stem cell transplantation has been extensively exploited as a therapeutic and research modality and has revolutionized current patient care. At present, more and more medical centers use peripheral blood progenitor cells for transplantation by mobilizing hematopoietic stem cells from bone marrow to peripheral blood because of potential ...
S, Fu, J, Liesveld
openaire +2 more sources
Current Biology, 1992
Recent studies indicate that hematopoietic stem cells that provide long-term reconstitution can be separated from more mature hematopoietic cells that provide radioprotection and short-term repopulation. With these findings it is now possible to design assays that will specifically measure long-term repopulating stem cells, as well as to develop ...
openaire +2 more sources
Recent studies indicate that hematopoietic stem cells that provide long-term reconstitution can be separated from more mature hematopoietic cells that provide radioprotection and short-term repopulation. With these findings it is now possible to design assays that will specifically measure long-term repopulating stem cells, as well as to develop ...
openaire +2 more sources
Heterogeneity of hematopoietic stem cells
Current Opinion in Immunology, 1993Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.
N, Uchida +3 more
openaire +2 more sources
Hematopoietic Stem Cells and Aging
Experimental Gerontology, 1999The question of whether hematopoietic stem cells are altered in aging has been the subject of considerable controversy for over two decades. The substantial advancement of knowledge on hematopoietic stem cells and developmental hematology in the last few years has reopened this issue for critical analysis.
openaire +2 more sources