Results 101 to 110 of about 1,162,311 (403)

Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

Stem Cells International, 2017
Mesenchymal stem/stromal cells (MSCs) from bone marrow (BM) have been used in coculture systems as a feeder layer for promoting the expansion of hematopoietic progenitor cells (HPCs) for hematopoietic cell transplantation.
Guadalupe R. Fajardo-Orduña, Héctor Mayani, Patricia Flores-Guzmán, Eugenia Flores-Figueroa, Erika Hernández-Estévez, Marta Castro-Manrreza, Patricia Piña-Sánchez, Lourdes Arriaga-Pizano, Alejandro Gómez-Delgado, Alarcón-Santos Guadalupe, Odette Balvanera-Ortíz, Juan J. Montesinos   +11 more
doaj   +1 more source

Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver

Haematologica, 2009
Background Hematopoietic progenitors are generated in the yolk sac and aorta-gonad-mesonephros region during early mouse development. At embryonic day 10.5 the first hematopoietic stem cells emerge in the aorta-gonad-mesonephros.
Claudia Orelio, Marian Peeters, Esther Haak, Karin van der Horn, Elaine Dzierzak   +4 more
doaj   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS, Douni E., MARCHETTI, Luigi, SABBIETI, Maria Giovanna   +3 more
core   +1 more source

CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells

Frontiers in Immunology, 2015
CD44 is an adhesion molecule that varies in size due to glycosylation and insertion of so-called variant exon products. The CD44 standard isoform (CD44s) is highly expressed in many cells and most abundantly in cells of the hematopoietic system, whereas ...
M. Zöller
semanticscholar   +1 more source

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Reduced hematopoietic stem cell frequency predicts outcome in acute myeloid leukemia

Haematologica, 2017
In patients with acute myeloid leukemia and low percentages of aldehyde-dehydrogenase-positive cells, non-leukemic hematopoietic stem cells can be separated from leukemic cells.
Wenwen Wang, Thomas Stiehl, Simon Raffel, Van T. Hoang, Isabel Hoffmann, Laura Poisa-Beiro, Borhan R. Saeed, Rachel Blume, Linda Manta, Volker Eckstein, Tilmann Bochtler, Patrick Wuchter, Marieke Essers, Anna Jauch, Andreas Trumpp, Anna Marciniak-Czochra, Anthony D. Ho, Christoph Lutz   +17 more
doaj   +1 more source

Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1

eLife, 2015
Hematopoietic stem cells (HSCs) are maintained by a perivascular niche in bone marrow but it is unclear whether the niche is reciprocally regulated by HSCs.
B. Zhou, Lei Ding, S. Morrison
semanticscholar   +1 more source

Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices

Advanced Healthcare Materials, EarlyView.
Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco, Zhibing Zhang, Neil M. Eisenstein, Nigel Tai, Liam M. Grover   +4 more
wiley   +1 more source

P323: STREAMLINING PRECLINICAL IN VIVO TREATMENT TRIALS BY MULTIPLEXING GENETICALLY LABELLED PDX MODELS OF SEVERAL PATIENTS IN A SINGLE MOUSE

HemaSphere, 2022
K. Hunt, D. Amend, R. Ludwig, B. Vick, A. K. Wirth, T. Herold, I. Jeremias   +6 more
doaj   +1 more source

U-shaped association of the stress hyperglycemia ratio with all-cause mortality and premature death in patients with cardiovascular disease: a cohort study

Diabetology & Metabolic Syndrome
Background The stress hyperglycemia ratio (SHR) is recognized as a significant indicator of relative hyperglycemia that has demonstrated to correlate with poor outcomes, including elevated mortality rates in individuals facing severe acute conditions ...
Na Wang, Ya Shao, Yan Zhan, Meiling Shao, Bin Liu, Longti Li, Huiqin Zhong   +6 more
doaj   +1 more source