Results 101 to 110 of about 1,175,170 (409)

CXCR4 pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis [PDF]

, 2008
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
CAMPIONI, Diana, CUNEO, Antonio, Ferrari, L, FOTINIDI, Maria, LA CORTE, Renato, LANZA, Francesco, LO MONACO, Andrea, Moretti, S, TROTTA, Francesco   +8 more
core   +2 more sources

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

DNA Damage in Circulating Hematopoietic Progenitor Stem Cells as Promising Biological Sensor of Frailty [PDF]

, 2022
Chiara Grasselli, Silvia Bombelli, Stefano Eriani, Giulia Domenici, Riccardo Galluccio, Chiara Tropeano, Marco Schmidt, Maddalena M. Bolognesi, B Torsello, Cristina Bianchi, Laura Antolini, Fábio Rossi, Paolo Mazzola, Valerio Leoni, Giuseppe Bellelli, R Perego   +15 more
openalex   +1 more source

The Role of Sp1 and Sp3 Transcription Factors in Hematopoiesis [PDF]

, 2013
Hematopoiesis is the generation of all mature blood cells from a rare pool of hematopoietic stem cells (HSCs). These blood cells serve a variety of essential functions in the vertebrate body, including gas transport, defense against pathogens, blood ...
Kulu, D.I. (Divine)
core   +1 more source

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Alexander Thompson, Belotti D, Buske C, Deschamps J, Edwina Dobbin, Glenda J. Dickson, Helen Wheadon, Joanne M. Ramsey, Lawrence HJ, Pamela M. Corrigan, Robin W. Freeburn   +10 more
core   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source

TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy

Epigenetics
Methylation modifications play pertinent roles in regulating gene expression and various biological processes. The silencing of the demethylase enzyme TET1 can affect the expressions of key oncogenes or tumour suppressor genes, thus contributing to ...
Ji Ren, Xiuying Chen, Jing Li, Yuxin Zan, Shan Wang, Yujie Tan, Yan Ding   +6 more
doaj   +1 more source

Human Mesenchymal Stem/Stromal Cells from Umbilical Cord Blood and Placenta Exhibit Similar Capacities to Promote Expansion of Hematopoietic Progenitor Cells In Vitro

Stem Cells International, 2017
Mesenchymal stem/stromal cells (MSCs) from bone marrow (BM) have been used in coculture systems as a feeder layer for promoting the expansion of hematopoietic progenitor cells (HPCs) for hematopoietic cell transplantation.
Guadalupe R. Fajardo-Orduña, Héctor Mayani, Patricia Flores-Guzmán, Eugenia Flores-Figueroa, Erika Hernández-Estévez, Marta Castro-Manrreza, Patricia Piña-Sánchez, Lourdes Arriaga-Pizano, Alejandro Gómez-Delgado, Alarcón-Santos Guadalupe, Odette Balvanera-Ortíz, Juan J. Montesinos   +11 more
doaj   +1 more source

Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver

Haematologica, 2009
Background Hematopoietic progenitors are generated in the yolk sac and aorta-gonad-mesonephros region during early mouse development. At embryonic day 10.5 the first hematopoietic stem cells emerge in the aorta-gonad-mesonephros.
Claudia Orelio, Marian Peeters, Esther Haak, Karin van der Horn, Elaine Dzierzak   +4 more
doaj   +1 more source

CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells

Frontiers in Immunology, 2015
CD44 is an adhesion molecule that varies in size due to glycosylation and insertion of so-called variant exon products. The CD44 standard isoform (CD44s) is highly expressed in many cells and most abundantly in cells of the hematopoietic system, whereas ...
M. Zöller
semanticscholar   +1 more source