Results 121 to 130 of about 217,775 (266)

Aging of hematopoietic stem cells is inconsequential to progenitor cell function. [PDF]

Stem Cell Reports
Myers J, Worthington AK, Poscablo DM, Medina P, Chattopadhyaya S, Mogharrab R, Rommel MGE, Forsberg EC.   +7 more
europepmc   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source

Oncogenesis as an Adverse Effect of Gene Replacement Therapy in Hematopoietic Stem Cells. [PDF]

Int J Mol Sci
Petrova IO, Smirnikhina SA.
europepmc   +1 more source

Development of Versatile Nanoparticle System for Efficient Drug Delivery into Pulmonary Endothelium

Advanced Science, EarlyView.
Pediatric acute respiratory distress syndrome (PARDS) suppresses the FOXF1 transcription factor and disrupts lung development. This study shows that the FOXF1‐activating small‐molecule compound, TanFe[F], can be precisely delivered to lung endothelial cells using the innovative LEDD nanoparticle system.
Afzaal N. Mohammed, Zicheng Deng, Arnab Misra, Marcus Orzabal, Ananya Kondapally, Enhong Li, Jonathan Do, Ying‐Wei Lan, Fatemeh Kohram, Hunter Blackburn, Andreas Damianos, Tanya V. Kalin, Vladimir V. Kalinichenko   +12 more
wiley   +1 more source

Human length telomeres restrict the regenerative potential of hematopoietic stem cells in mice. [PDF]

J Biol Chem
Rowe MM, Tober J, Ortiz V, Smoom R, Tzfati Y, Speck N, Kaestner KH.   +6 more
europepmc   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Hematopoietic (stem) cells-The elixir of life? [PDF]

FEBS Lett
Cerezo EL, Anderson J, Vedrenne ED, Martín NY, Lengefeld J.   +4 more
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Glycosylation orchestrates megakaryocytic fate of hematopoietic stem cells via Wnt-MUC13 signaling. [PDF]

Nat Commun
Roisman A, Rivadeneyra L, Conroy L, Weich N, Steenackers A, Lee-Sundlov MM, Glabere S, Zheng S, Rosenbalm KE, Zogg M, Steinhardt G, Veltri AJ, Lau JTY, Zielonka M, Zielonka J, Fadda E, Gu T, Weiler H, Sun RC, Hoffmeister KM.   +19 more
europepmc   +1 more source

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao, Riccardo Tognato, Micaela Natta, Elena Della Bella, Alessandro Cianciosi, Tiziano Serra   +5 more
wiley   +1 more source