Results 301 to 310 of about 1,207,844 (359)
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
Cell, 2016 Toshihiko Oki, Borja Saez, Xin Wang
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New England Journal of Medicine, 1979
(First of Three Parts) IN man, most tissues consist primarily of differentiated cells that normally show little evidence of proliferation and self-renewal.
P, Quesenberry, L, Levitt
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(First of Three Parts) IN man, most tissues consist primarily of differentiated cells that normally show little evidence of proliferation and self-renewal.
P, Quesenberry, L, Levitt
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Clinical Orthopaedics and Related Research, 2000
Hematopoietic stem cells are rare cells found in the bone marrow, peripheral blood, placenta, and elsewhere that sustain the hematopoietic system. The current review will focus on the evolving views of the biology of these cells. Because hematopoietic stem cells have been studied and transplanted for several decades, lessons learned from studying these
C, Smith, B, Storms
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Hematopoietic stem cells are rare cells found in the bone marrow, peripheral blood, placenta, and elsewhere that sustain the hematopoietic system. The current review will focus on the evolving views of the biology of these cells. Because hematopoietic stem cells have been studied and transplanted for several decades, lessons learned from studying these
C, Smith, B, Storms
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Cancer Investigation, 2002
In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
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In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
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Characterization of Hematopoietic Stem Cells
Annals of the New York Academy of Sciences, 1995On the basis of density-separated mononuclear cells isolated from bone marrow, peripheral blood, and cord blood, we have repeatedly shown good correlation between two-color flow cytometric (FACS) CD34 analysis and colony formation in the clonogenic assay.
G, Fritsch +7 more
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Current Opinion in Immunology, 2014
Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
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Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
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Pediatrics, 2004
The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
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The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
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Birth Defects Research Part C: Embryo Today: Reviews, 2003
AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
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AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
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2013
Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
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Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
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Mobilization of hematopoietic stem cells
Blood Reviews, 2000Hematopoietic stem cell transplantation has been extensively exploited as a therapeutic and research modality and has revolutionized current patient care. At present, more and more medical centers use peripheral blood progenitor cells for transplantation by mobilizing hematopoietic stem cells from bone marrow to peripheral blood because of potential ...
S, Fu, J, Liesveld
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