Repurposing of an inotropic drug dobutamine to enhance the production of human hematopoietic stem cells from human induced pluripotent stem cells. [PDF]
Laowtammathron C +5 more
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Research and analysis of differential gene expression in CD34 hematopoietic stem cells in myelodysplastic syndromes. [PDF]
Wang MX +5 more
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Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells. [PDF]
Conti A +20 more
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BST2 facilitates activation of hematopoietic stem cells through ERK signaling. [PDF]
Florez MA +11 more
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Single-cell dynamic RNA and glycosylation sequencing reveals the mechanism underlying the differentiation of pluripotent stem cells into hematopoietic stem cells. [PDF]
Feng W +8 more
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Selection of pre-leukemic hematopoietic stem cells driven by distinct extracellular matrix molecules
Jassinskaja M +27 more
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Hematopoietic Stem Cells and Regeneration
Cold Spring Harbor Perspectives in Biology, 2021Hematopoietic stem cell (HSC) regeneration is the remarkable process by which extremely rare, normally inactive cells of the bone marrow can replace an entire organ if called to do so by injury or harnessed by transplantation. HSC research is arguably the first quantitative single-cell science and the foundation of adult stem cell biology.
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