Results 151 to 160 of about 4,670 (184)

Hematoporphyrin monomethyl ether-mediated photodynamic therapy inhibits the growth of keloid graft by promoting fibroblast apoptosis and reducing vessel formation

Photochemical and Photobiological Sciences, 2020
Photodynamic therapy (PDT) has been shown to significantly inhibit fibroblast activity. However, the effect of PDT mediated by the photosensitizer hematoporphyrin monomethyl ether (HMME) on keloids is not known well.
Xiaomei Cui, Jing Zhu, Xiao-yan Wu, Shengju Yang, Xiaodong Yao, Wenyan Zhu, P. Xu, Xiaodong Chen   +7 more
semanticscholar   +1 more source

Binding Interactions of Hematoporphyrin Monomethyl Ether with Bovine Serum Albumin

2008 IEEE PhotonicsGlobal@Singapore, 2008
Hematoporphyrin monomethyl ether (HMME) that is the second generation photosensitizers is a new and promising porphyrin related photosensitizer for photodynamic therapy and diagnosis in certain tumor. The binding of HMME to bovine serum albumin (BSA) in aqueous solution was studied using fluorescence spectra and absorption spectra.
Shangyuan Feng, Juqiang Lin, Yongzeng Li, Zufang Huang, Rong Chen   +4 more
openaire   +1 more source

Effect of hematoporphyrin monomethyl ether‐mediated photodynamic therapy on hypertrophic scar fibroblasts

Photodermatology, Photoimmunology & Photomedicine, 2011
Background: Clinical studies have demonstrated that photodynamic therapy (PDT) for hyperplastic dermatosis results in a beneficial outcome. Hypertrophic scar (HS) is a pathological process characterized by fibroblastic hyperproliferation. However, it is unclear whether photochemical interactions between PDT and fibroblasts contribute to a beneficial ...
Hong, Cai, Ying, Gu, Qiang, Sun, Jing, Zeng, Ning, Dong, Guang, Zhao   +5 more
openaire   +2 more sources

Bactericidal effects of hematoporphyrin monomethyl ether-mediated photosensitization against pathogenic communities from supragingival plaque

Applied Microbiology and Biotechnology, 2013
Photodynamic antimicrobial chemotherapy (PACT) is proposed as a potential candidate to inactivate pathogens in localized infections due to the rapid evolution of bacterial resistance. The treatment modality utilizes nontoxic agents called photosensitizers and harmless visible light to generate reactive oxygen species which result in microbial cells ...
Yi, Sun, Defeng, Xing, Lanhua, Shen, Miao, Sun, Ming, Fang, Liangjia, Bi, Yanjiao, Sui, Zhiguo, Zhang, Wenwu, Cao   +8 more
openaire   +3 more sources

Bioengineered Escherichia coli Nissle 1917 with hematoporphyrin monomethyl ether for targeted sonodynamic therapy and immune activation in ovarian cancer.

Journal of materials chemistry. B
Ovarian cancer remains one of the most lethal gynecological malignancies worldwide. Sonodynamic therapy (SDT) offers a non-invasive treatment modality.
Yue Pei, Huan Yi, Lingsi Chen, X. Zheng, Bo Liu   +4 more
semanticscholar   +1 more source

Comparison of Two Generation Photosensitizers of PsD-007 and Hematoporphyrin Monomethyl Ether Photodynamic Therapy for Treatment of Port-Wine Stain: A Retrospective Study

Photobiomodulation, photomedicine, and laser surgery, 2019
Objective: To compare the efficacy and safety of the two generation photosensitizers, PsD-007 and hematoporphyrin monomethyl ether (HMME), for photodynamic therapy (PDT) of port-wine stain (PWS).
G. Ma, Yue Han, Hanru Ying, Xiaolin Zhang, Wenxin Yu, Jiafang Zhu, Qingqing Cen, Hui Chen, Yunbo Jin, Xiaoxi Lin   +9 more
semanticscholar   +1 more source

Clinical efficacy of hematoporphyrin monomethyl ether-based photodynamic therapy for the treatment of port-wine stain and its sonographic changes

Chinese Journal of Dermatology, 2019
Objective To evaluate the clinical efficacy of hematoporphyrin monomethyl ether-based photodynamic (HMME-PDT) therapy for the treatment of port-wine stain (PWS) and its sonographic changes.
Mi Sheng, Fang Wang, Ru-Zhi Zhang, Chong Wang, Liping Xiao, Yu-hua Yang, Yan Li, Chun-xing Xu, Xiaoming Liu   +8 more
semanticscholar   +1 more source

Ultrasound-triggered breast tumor sonodynamic therapy through hematoporphyrin monomethyl ether-loaded liposome.

Journal of biomedical materials research. Part B, Applied biomaterials, 2021
Sonodynamic therapy (SDT) which employs ultrasound-triggered sonosensitizers to generate reactive oxygen species (ROS) has been proved to be effective for treatment of cancers. However, it is still desirable for sonosensitizers to be delivered to tumors as effectively as possible.
Yi, Zhang, Yulong, Ou, Jia, Guo, Xiaojia, Huang   +3 more
openaire   +1 more source

Preliminary study of optical properties of hematoporphyrin monomethyl ether (HMME), a new PDT sensitizer

SPIE Proceedings, 2010
We report on some of the optical properties of hematoporphyrin monomethyl ether (HMME), a relatively new photosensitizer that has been in clinical trials in China since the early 1990s. We characterized the photosensitizer on the basis of one photon absorption and emission.
Gregory F. Glazner, Tim C. Lei, Larry Scherrer, Srinivas Pendyala, Michael Duffy, Xiuli Wang, Hongwei Wang, Fred W. Hetzel, Zheng Huang   +8 more
openaire   +1 more source

Sonodynamic cytotoxic effect of hematoporphyrin monomethyl ether on C6 glioma cells - in vitro study

SPIE Proceedings, 2007
Objectives: To study the cytotoxicity induced by photosensitizer mediated sonodynamic effects on c6 glioma cells in vitro and to lay the experimental foundation for the sonodynamic therapy (SDT) of glioma tumor. Methods: A domestic photosensitizer hematoporphyrin monomethyl ether (HMME) was used as the sensitizer.
Wu Yue, Da-yong Song, Zhao Zhao, Shao-dong Cao, Xiang-xi Meng, Xu Zhang, Zheng Huang   +6 more
openaire   +1 more source