Results 91 to 100 of about 274 (132)
Hematoporphyrin Photoradiation Therapy for Iris Neovascularization
Photoradiation therapy is a new technique currently under clinical investigation for the treatment of a variety of solid malignant tumors. The technique involves intravenous (IV) administration of hematoporphyrin derivative, a photosensitizing compound that is preferentially retained by malignant cells, and photoactivation of a neoplasm with red light (
Andrew J Packer, S S Hayreh, David T Tse
exaly +6 more sources
Hematoporphyrin Photoradiation Therapy for Intraocular and Orbital Malignant Melanoma
Photoradiation therapy (PRT) is a new technique that is currently under investigation for the treatment of a variety of solid malignant tumors. The technique involves systemic administration of hematoporphyrin derivative (HpD), a photosensitizing compound that is preferentially retained by malignant cells and photoactivation of the neoplasm with red ...
Thomas A Weingeist +2 more
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Hematoporphyrin derivative photoradiation therapy in murine solid tumors
The cytocidal activity of light-activated hematoporphyrin derivative (Hpd) in experimental and human tumors is under investigation in many laboratories. This activity is based upon preferential incorporation of Hpd in malignant tissues and its photosensibilization by red light. Treatment of mice bearing MS-2 fibrosarcoma and B16 melanoma, a metastastic
G Canti, A Andreoni, A Nicolin
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The effects of Hematoporphyrin Derivative Photoradiation Therapy (HpD-PRT) on Greene's amelanotic melanoma implanted into the anterior chamber of rabbits have been examined by biomicroscopy, fluorescein angiography and histopathology. The tumors were irradiated 24 hours after injection of HpD when both the porphyrin concentration and the porphyrin ...
J L Van Delft +2 more
exaly +4 more sources
Hematoporphyrin Derivative Photoradiation Therapy
To the Editor. —I read with interest the article in the JulyArchivesregarding hematoporphyrin derivatives in photoradiation therapy. 1 I found a number of references to this subject appearing in the literature. When I introduced porphyrins to clinical medicine in 1955, at the Johns Hopkins Hospital, Baltimore, 2 I originally used it as a surgical tool.
D. R. Taxdal
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Bactericidal Effects of Photoradiation Therapy With Hematoporphyrin Derivative
Hematoporphyrin derivative (Hpd) localizes selectively in malignant and rapidly metabolizing tissues and undergoes a cytotoxic reaction when exposed to light of a specific wavelength. Hpd has been studied extensively with regard to the diagnosis and treatment of tumors but not with regard to bactericidal activity. This investigation assessed the effect
F R, Venezio +6 more
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Hematoporphyrin-Derivative and Photoradiation Therapy of Malignant Tumors
Lasers in Surgery and Medicine, 1983AbstractKodak projectors with #2418 red Corning filters were used as a light source to treat cutaneous and subcutaneous malignancies in five patients who previously had been given hematoporphyrin derivative (HpD). An argon dye laser system was used to treat malignancies in patients who also were given the HpD.
James S Mccaughan, William Hicks
exaly +3 more sources
Intra-Abdominal Applications of Hematoporphyrin Photoradiation Therapy
At Roswell Park Memorial Institute (RPMI), long experience in the management of tumors with hematoporphyrin derivative (HPD) photoradiation therapy (PRT) has documented the destruction of a wide range of neoplasms with remarkable regularity (1,2). The surrounding inflammatory response and eschar that formed at the site of the tumor nodule indicated ...
H O, Douglass +6 more
openaire +3 more sources

