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Hematoporphyrin Derivative Photoradiation Therapy in Managing Nevoid Basal-Cell Carcinoma Syndrome
Archives of Ophthalmology, 1984 Hematoporphyrin derivative (HpD) is a photodynamically active dye that is preferentially retained by malignant tissues and initiates a cytotoxic reaction when exposed to red light. Normal tissues adjacent to a tumor retain HpD to a lesser degree and are thus spared damage from the light-induced reaction.
D T, Tse, R C, Kersten, R L, Anderson
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Clinics in Chest Medicine, 1985
In recent years hematoporphyrin derivative (HpD), a mixture of porphyrin compounds that have an increased affinity for malignant tissue, has been used as an endobronchial tumor indicator to facilitate the bronchoscopic localization of early squamous cell carcinoma of the central tracheobronchial tree. In this article the authors describe four different
Denis A Cortese
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In recent years hematoporphyrin derivative (HpD), a mixture of porphyrin compounds that have an increased affinity for malignant tissue, has been used as an endobronchial tumor indicator to facilitate the bronchoscopic localization of early squamous cell carcinoma of the central tracheobronchial tree. In this article the authors describe four different
Denis A Cortese
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AN ATOMIC BASIS OF CANCER—PHOTORADIATION THERAPY AND HEMATOPORPHYRIN DERIVATIVE
International Journal of PIXE, 1991The principles of photoradiation therapy employing a tumor-seeking agent such as a hematoporphyrin derivative are described. The properties and preparation of hematoporphyrin derivatives and metalloporphyrin synthesis are briefly summarized. We show that PIXE analysis can be used to indicate the degree of a synthesis.
CHAU-CHIN WEI, CHIH-SHANG WEI
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Current Eye Research, 1984
Cytotoxicity induced by hematoporphyrin derivative (HpD) photoradiation in both normal and experimental tumor tissue of pigmented rabbit eyes has been examined. In addition, documentation of HpD induced fluorescence in ocular structures has also been obtained.
James Jester +2 more
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Cytotoxicity induced by hematoporphyrin derivative (HpD) photoradiation in both normal and experimental tumor tissue of pigmented rabbit eyes has been examined. In addition, documentation of HpD induced fluorescence in ocular structures has also been obtained.
James Jester +2 more
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Bactericidal Effects of Photoradiation Therapy With Hematoporphyrin Derivative
Journal of Infectious Diseases, 1985Hematoporphyrin derivative (Hpd) localizes selectively in malignant and rapidly metabolizing tissues and undergoes a cytotoxic reaction when exposed to light of a specific wavelength. Hpd has been studied extensively with regard to the diagnosis and treatment of tumors but not with regard to bactericidal activity. This investigation assessed the effect
F R, Venezio +6 more
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Photoradiation Therapy. II. Cure of Animal Tumors With Hematoporphyrin and Light23
Journal of the National Cancer Institute, 1975T J Dougherty +2 more
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Exposure (dose) tables for hematoporphyrin derivative photoradiation therapy
Lasers in Surgery and Medicine, 1984AbstractTwo sets of tables are presented that permit the rapid determination of (1) milliwatts per centimter2 based upon known site diameter and power output from fiber optic and (2) time of exposure (minutes and seconds) based upon known site diameter and power output from fiber optic.
M W, Berns +3 more
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Hematoporphyrin Derivative and Laser Photoradiation in the Diagnosis and Treatment of Bladder Cancer
Journal of Urology, 1983Diagnosis and treatment of 8 patients with malignant bladder tumors were performed with intravenous administration of hematoporphyrin derivative, followed by krypton-ion laser violet light photoradiation and argon-dye laser red light photoradiation therapy.
A, Tsuchiya +5 more
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Hematoporphyrin Derivative Photoradiation Therapy, in Theory and in Practice
1984A patient has been referred to you for possible photoradiation therapy. She has breast cancer, treated in the past by bilateral mastectomy, radiotherapy, hormone therapy, and chemotherapy. It is now recurrent to the anterior, lateral, and posterior chest wall in the form of several hundred subcutaneous and cutaneous nodules ranging in diameter from 1 ...
J. C. Kennedy, K. Oswald
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Inhibition of mammalian DNA polymerases by hematoporphyrin derivative and photoradiation.
Cancer research, 1986Hematoporphyrin derivative (HPD) plus photoradiation caused the inactivation of DNA polymerases from calf thymus and R3230AC rat mammary tumor. Photosensitization of purified DNA polymerase-alpha as well as two forms of DNA polymerase-delta (I and II) from calf thymus were evaluated.
J J, Crute +5 more
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