Results 131 to 140 of about 735 (172)
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Hematoporphyrin Photoradiation Therapy for Iris Neovascularization
Archives of Ophthalmology, 1984Photoradiation therapy is a new technique currently under clinical investigation for the treatment of a variety of solid malignant tumors. The technique involves intravenous (IV) administration of hematoporphyrin derivative, a photosensitizing compound that is preferentially retained by malignant cells, and photoactivation of a neoplasm with red light (
A J, Packer +3 more
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Photoradiation Therapy. II. Cure of Animal Tumors With Hematoporphyrin and Light23
JNCI: Journal of the National Cancer Institute, 1975T. J. Dougherty +4 more
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Exposure (dose) tables for hematoporphyrin derivative photoradiation therapy
Lasers in Surgery and Medicine, 1984AbstractTwo sets of tables are presented that permit the rapid determination of (1) milliwatts per centimter2 based upon known site diameter and power output from fiber optic and (2) time of exposure (minutes and seconds) based upon known site diameter and power output from fiber optic.
M W, Berns +3 more
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Hematoporphyrin Derivative and Laser Photoradiation in the Treatment of Lung Cancer
Chest, 1982Photoradiation therapy (PRT) was performed in 13 lung cancer cases and in one case of severely atypical squamous metaplasia following administration of hematoporphyrin derivative (HpD). The HpD is activated by visible red light (630 nm, 90 to 400 mW) from an argon dye laser.
Y, Hayata +4 more
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Inhibition of mammalian DNA polymerases by hematoporphyrin derivative and photoradiation.
Cancer research, 1986Hematoporphyrin derivative (HPD) plus photoradiation caused the inactivation of DNA polymerases from calf thymus and R3230AC rat mammary tumor. Photosensitization of purified DNA polymerase-alpha as well as two forms of DNA polymerase-delta (I and II) from calf thymus were evaluated.
J J, Crute +5 more
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[Photoradiation therapy. The role of hematoporphyrin in the diagnosis and treatment of cancer].
Eric S. Edell, Díaz Jiménez
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Hematoporphyrin Derivative Photoradiation Therapy, in Theory and in Practice
1984A patient has been referred to you for possible photoradiation therapy. She has breast cancer, treated in the past by bilateral mastectomy, radiotherapy, hormone therapy, and chemotherapy. It is now recurrent to the anterior, lateral, and posterior chest wall in the form of several hundred subcutaneous and cutaneous nodules ranging in diameter from 1 ...
J. C. Kennedy, K. Oswald
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Immunological suppression in mice treated with hematoporphyrin derivative photoradiation.
Cancer research, 1986Hematoporphyrin derivative (HPD) is a potent photosensitizer which localizes preferentially in malignant tumors. Parenteral administration of this compound followed by irradiation with the appropriate wavelengths of light has been used for the diagnosis and treatment of various epithelial neoplasms.
C A, Elmets, K D, Bowen
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Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light.
Journal of the National Cancer Institute, 1975Exposure of mouse and rat tumors of various types to more than 600 nm light 24 or 48 hours after an injection of hematoporphyrin resulted in a substantial number of long-term cures. Since hematoporphyrin is preferentially retained in tumor tissue, selective tumor destruction could be obtained.
Dougherty, T J +4 more
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