Results 121 to 130 of about 1,492 (143)

Treatment of intraocular tumors with hematoporphyrin derivative photoradiation therapy.

Conference on Lasers and Electro-Optics, 1984
Hematoporphyrin derivative (HpD) photoradiation therapy (PRT) is currently being examined for the treatment of intraocular tumors. HpD is taken up in malignant tissue, and tumorcidal action can be induced when HpD is activated with visible red light. Preclinical studies have been performed to examine the pharmacology of HpD and the toxicology of HpD ...
Charles J. Gomer, A. Linn Murphree, Daniel R. Doiron, Nicholas J. Razum, Stanley W. Fountain   +4 more
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Hematoporphyrin Derivative Photoradiation Therapy of Endobronchial Lung Cancer

1984
Hematoporphyrin derivative (HpD) photoradiation therapy (PRT) has been reported as an effective treatment for a variety of tumors (1,2). This technique relys on the tumor localizing and photosensitization potential of HpD to selectively destroy tumors.
Daniel R. Doiron, Oscar J. Balchum
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Photoradiation Therapy with Hematoporphyrin Derivative in the Management of Brain Tumors

1986
Hematoporphyrin is a naturally occurring compound similar to the heme of hemoglobin without the iron ligand (Fig. 1). Since the observation by Lipson44–46 in 1960 that a derivative of hematoporphyrin (HpD) had superior tumor localizing characteristics when compared to hematoporphyrin, all subsequent clinical studies have used HpD.
Robert E. Wharen, Robert E. Anderson, Edward R. Laws   +2 more
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Photoradiation Therapy with Hematoporphyrin as a Selective Technique for the Treatment of Malignant Tumors

1985
Photoradiation therapy (properly, the technique should be classified as photochemotherapy) is a new branch of oncology for the treatment of malignant tumors. The method is based on the ability of certain porphyrins[1–3] to be taken up and/or retained by tumor cells for longer periods of time than normal cells.
L. Tomio, F. Calzavara, G. Jori
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Immunological suppression in mice treated with hematoporphyrin derivative photoradiation.

Cancer research, 1986
Hematoporphyrin derivative (HPD) is a potent photosensitizer which localizes preferentially in malignant tumors. Parenteral administration of this compound followed by irradiation with the appropriate wavelengths of light has been used for the diagnosis and treatment of various epithelial neoplasms.
C A, Elmets, K D, Bowen
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Photoradiation Therapy with Hematoporphyrin Derivative and an Argon Dye Laser of Bladder Carcinoma

1984
Hematoporphyrin Derivative (HpD) which has an affinity for malignant tumors is excited by light exposure and reacts photodynamically in tumor tissue. Therefore it is possible to treat malignant tumor selectively without any damage to surrounding normal tissues. HpD is excited by a light in the spectrum from ultraviolet to visible red.
Tetsutaro Ohi, Harubumi Kato, Akira Tsuchiya, Nobuo Obara, Koichi Imamura, Katsuo Aizawa, Chimori Konaka, Jutaro Ono, Norihiko Kawate, Kazuo Yoneyama, Makoto Saito, Hidenobu Takahashi, Sumiyaki Tsukimura, Hideki Shinohara, Johnson Lay, Yoshihiro Hayata   +15 more
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Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light.

Journal of the National Cancer Institute, 1975
Exposure of mouse and rat tumors of various types to more than 600 nm light 24 or 48 hours after an injection of hematoporphyrin resulted in a substantial number of long-term cures. Since hematoporphyrin is preferentially retained in tumor tissue, selective tumor destruction could be obtained.
Dougherty, T J, Grindey, G B, Fiel, R, Weishaupt, K R, Boyle, D G   +4 more
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Hematoporphyrin Derivative Photoradiation Therapy Applied in Gynecology

Journal of Gynecologic Surgery, 1986
HELMUT F. SCHELLHAS, DAVID F. SCHNEIDER
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The acute effects of hematoporphyrin derivative photoradiation on tumor and liver capillary blood flow.

Microcirculation, endothelium, and lymphatics, 1991
The acute effects of photoradiation after administering hematoporphyrin derivative (Hpd) on capillary blood flow were studied in intrahepatic tumors and normal liver. The tumors were solitary Walker carcinosarcomas implanted within the livers of Sprague-Dawley rats.
R, Jacobs, N B, Ackerman, N D, Bloom, D D, Kim   +3 more
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[Clinical studies on photoradiation therapy with hematoporphyrin derivatives (HpD) and argon dye laser].

Nihon Sanka Fujinka Gakkai zasshi, 1986
Photoradiation therapy (PRT), in which hematoporphyrin derivatives (HpD) are activated by an argon-dye laser, was performed on superficial or subcutaneous tumors in 4 vulvar carcinoma, 1 vaginal carcinoma, 1 invasive cervical carcinoma and 8 carcinoma in situ (CIS) of the uterine cervix.
K, Kubota, T, Kasai, H, Iwasaki, H, Takamizawa   +3 more
openaire   +1 more source