Results 101 to 110 of about 274 (132)
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Laser photoradiation therapy of cancer following hematoporphyrin sensitization
Lasers in Surgery and Medicine, 1982AbstractHematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) of human malignancy has been performed on 267 tumor sites in 50 patients. Tumor response has been assayed at 24 hours and one month following treatment with 625–635 nm light from an argon laser‐pumped dye laser.
Alan G Wile, Michael W Berns
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Evaluation of hematoporphyrin photoradiation therapy to treat choroidal melanomas
Lasers in Surgery and Medicine, 1984AbstractHematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) was used to treat choroidal melanomas in 23 human subjects. Tumor sizes were divided into three categories: less than 500 mm3 (11 patients), 500‐1,000 mm3 (four patients), and greater than 1,000 mm3 (eight patients). Tumors were exposed to 630 nm laser light at total doses of 300‐3,000
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Hematoporphyrin derivative and photoradiation therapy in early stage lung cancer
Lasers in Surgery and Medicine, 1984AbstractPhotoradiation therapy (PDT) with administration of hematoporphyrin derivative (HPD) was performed in ten cases of early stage central‐type lung cancer of which six cases were treated by PRT alone due to inoperability because of poor pulmonary function I five and refusal of surgery on one. Four cases were resected after PRT.
Yoshihiro Hayata +2 more
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Photoradiation of rabbit ocular malignant melanoma sensitized with hematoporphyrin derivative
Current Eye Research, 1984Photoradiation therapy (PRT) against the Greene-Harvey amelanotic malignant melanoma on the rabbit iris was effectively used to cause tumor regression. A dose of 2.5 mg/kg of hematoporphyrin derivative (HPD) given intravenously, followed by photoradiation at a wavelength of 632 nm and a power density as low as 71 mW/cm2 for 24 minutes (102 J/cm2) was ...
Theodore W Séry +2 more
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Hematoporphyrin Derivative and Laser Photoradiation in the Diagnosis and Treatment of Bladder Cancer
Journal of Urology, 1983 Diagnosis and treatment of 8 patients with malignant bladder tumors were performed with intravenous administration of hematoporphyrin derivative, followed by krypton-ion laser violet light photoradiation and argon-dye laser red light photoradiation therapy.
A, Tsuchiya +5 more
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Hematoporphyrin Derivative Photoradiation Therapy, in Theory and in Practice
, 1984 A patient has been referred to you for possible photoradiation therapy. She has breast cancer, treated in the past by bilateral mastectomy, radiotherapy, hormone therapy, and chemotherapy. It is now recurrent to the anterior, lateral, and posterior chest wall in the form of several hundred subcutaneous and cutaneous nodules ranging in diameter from 1 ...
J. C. Kennedy, K. Oswald
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Treatment of intraocular tumors with hematoporphyrin derivative photoradiation therapy.
Conference on Lasers and Electro-Optics, 1984 Hematoporphyrin derivative (HpD) photoradiation therapy (PRT) is currently being examined for the treatment of intraocular tumors. HpD is taken up in malignant tissue, and tumorcidal action can be induced when HpD is activated with visible red light. Preclinical studies have been performed to examine the pharmacology of HpD and the toxicology of HpD ...
Charles J. Gomer +4 more
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Hematoporphyrin Derivative Photoradiation Therapy in Managing Nevoid Basal-Cell Carcinoma Syndrome
Archives of Ophthalmology, 1984 Hematoporphyrin derivative (HpD) is a photodynamically active dye that is preferentially retained by malignant tissues and initiates a cytotoxic reaction when exposed to red light. Normal tissues adjacent to a tumor retain HpD to a lesser degree and are thus spared damage from the light-induced reaction.
D T, Tse, R C, Kersten, R L, Anderson
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DNA damage and repair in CHO cells following hematoporphyrin photoradiation
Cancer Letters, 1980The induction and repair of alkali labile lesions and single strand breaks in DNA of CHO cells following HpD photoradiation of X-irradiation has been examined. For treatments producing equal survival levels, the amount of DNA damage was less for HpD-photoradiated cells compared to X-irradiated cells.
Charles J Gomer
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Photoradiation Therapy with Hematoporphyrin Derivative in Early and Stage 1 Lung Cancer
Chest, 1984Photoradiation therapy with hematoporphyrin derivative was used in 13 cases of early-stage and eight cases of stage 1 central-type lung cancer. The lesions were photoradiated superficially or interstitially by an argon dye laser with a power of 80 to 600 mW for 10 to 40 minutes at 48 hours or more after intravenous injection of 2.5 to 5.0 mg of ...
Yoshihiro Hayata +2 more
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