Results 101 to 110 of about 1,492 (143)
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Hematoporphyrin-Derivative and Photoradiation Therapy of Malignant Tumors
Lasers in Surgery and Medicine, 1983AbstractKodak projectors with #2418 red Corning filters were used as a light source to treat cutaneous and subcutaneous malignancies in five patients who previously had been given hematoporphyrin derivative (HpD). An argon dye laser system was used to treat malignancies in patients who also were given the HpD.
J S McCaughan
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Laser photoradiation therapy of cancer following hematoporphyrin sensitization
Lasers in Surgery and Medicine, 1982AbstractHematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) of human malignancy has been performed on 267 tumor sites in 50 patients. Tumor response has been assayed at 24 hours and one month following treatment with 625–635 nm light from an argon laser‐pumped dye laser.
Michael Berns
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Evaluation of hematoporphyrin photoradiation therapy to treat choroidal melanomas
Lasers in Surgery and Medicine, 1984AbstractHematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) was used to treat choroidal melanomas in 23 human subjects. Tumor sizes were divided into three categories: less than 500 mm3 (11 patients), 500‐1,000 mm3 (four patients), and greater than 1,000 mm3 (eight patients). Tumors were exposed to 630 nm laser light at total doses of 300‐3,000
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Hematoporphyrin derivative and photoradiation therapy in early stage lung cancer
Lasers in Surgery and Medicine, 1984AbstractPhotoradiation therapy (PDT) with administration of hematoporphyrin derivative (HPD) was performed in ten cases of early stage central‐type lung cancer of which six cases were treated by PRT alone due to inoperability because of poor pulmonary function I five and refusal of surgery on one. Four cases were resected after PRT.
J Ono, C Konaka, Y Hayata
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Photoradiation of rabbit ocular malignant melanoma sensitized with hematoporphyrin derivative
Current Eye Research, 1984Photoradiation therapy (PRT) against the Greene-Harvey amelanotic malignant melanoma on the rabbit iris was effectively used to cause tumor regression. A dose of 2.5 mg/kg of hematoporphyrin derivative (HPD) given intravenously, followed by photoradiation at a wavelength of 632 nm and a power density as low as 71 mW/cm2 for 24 minutes (102 J/cm2) was ...
T J Dougherty
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Hematoporphyrin Derivative and Laser Photoradiation in the Treatment of Lung Cancer
Chest, 1982Photoradiation therapy (PRT) was performed in 13 lung cancer cases and in one case of severely atypical squamous metaplasia following administration of hematoporphyrin derivative (HpD). The HpD is activated by visible red light (630 nm, 90 to 400 mW) from an argon dye laser.
J Ono, Jutaro Ono, C Konaka
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Intra-Abdominal Applications of Hematoporphyrin Photoradiation Therapy
, 1983 At Roswell Park Memorial Institute (RPMI), long experience in the management of tumors with hematoporphyrin derivative (HPD) photoradiation therapy (PRT) has documented the destruction of a wide range of neoplasms with remarkable regularity (1,2). The surrounding inflammatory response and eschar that formed at the site of the tumor nodule indicated ...
H O, Douglass +6 more
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DNA damage and repair in CHO cells following hematoporphyrin photoradiation
Cancer Letters, 1980The induction and repair of alkali labile lesions and single strand breaks in DNA of CHO cells following HpD photoradiation of X-irradiation has been examined. For treatments producing equal survival levels, the amount of DNA damage was less for HpD-photoradiated cells compared to X-irradiated cells.
Charles J Gomer
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Photoradiation Therapy with Hematoporphyrin Derivative in Early and Stage 1 Lung Cancer
Chest, 1984Photoradiation therapy with hematoporphyrin derivative was used in 13 cases of early-stage and eight cases of stage 1 central-type lung cancer. The lesions were photoradiated superficially or interstitially by an argon dye laser with a power of 80 to 600 mW for 10 to 40 minutes at 48 hours or more after intravenous injection of 2.5 to 5.0 mg of ...
J Ono, Jutaro Ono, C Konaka
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Hematoporphyrin derivative photoradiation therapy of the rat 9L gliosarcoma brain tumor model
Lasers in Surgery and Medicine, 1984AbstractThe distribution of hematoporphyrin derivative (HPD) in the rat 9L gliosarcoma intracerebral brain tumor model at 4, 24, 48, and 72 hours after intravenous administration was evaluated using a digital video fluorescence microscopy technique. Maximum tissue fluorescence in the normal brain was observed at 4 hours, whereas maximum fluorescence in
Michael Berns, M S Edwards
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