HEMATOPORPHYRIN DERIVATIVE AND PHOTORADIATION IN THE DIAGNOSIS AND TREATMENT OF BLADDER CANCER [PDF]
Akira Tsuchiya +9 more
openaire +3 more sources
Effectiveness of Laser Photoradiation Therapy following Hematoporphyrin Derivative Administration in the Experimental MS-2 Tumor Model [PDF]
The effectiveness of laser photoradiation therapy with hematoporphyrin derivative sensitization was tested in the MS-2 sarcoma. This solid tumor, transplanted into the pad of the hind leg of BALB/c mice, was found to be a sensitive experimental model ...
Renato Marchesini +6 more
core +1 more source
Photoradiation Therapy for Cutaneous and Subcutaneous Malignancies [PDF]
Photoradiation therapy (PRT) using hematoporphyrin derivative (Hpd) as the photosensitizing agent is being developed for local treatment of a wide variety of malignant lesions including those involving the skin.
Dougherty, Thomas J.
core +1 more source
Photoradiation therapy of gynecologic malignancies [PDF]
Four patients with gynecologic tumors recurrent either to the vagina or skin were treated with photoradiation therapy. A cytotoxic effect on the tumor was achieved by injecting hematoporphyrin derivative intravenously followed by exposing the treatment ...
DiSaia, Philip J +4 more
core +1 more source
Hyperthermal Effects in Phototherapy with Hematoporphyrin Derivative Sensitization [PDF]
Although the photochemical reaction of hematoporphyrin derivative (HpD) appears to play a major role in cytotoxic activity, the hyperthermal contribution to tumor destruction has not yet been clarified.
Renato Marchesini +7 more
core +1 more source
Mutagenicity in human bladder cancer cell line exposed to hematoporphyrin derivative photoradiation and ultraviolet Radiation [PDF]
ヒト膀胱癌由来培養細胞株KKー47細胞よりHAT selectoonにて得られた細胞株は細胞感染が認められ,野性型細胞を用いて本研究を逐行した。光感受性物質はHpDI(Queen Elizabeths Hospital,Australia)を,培養液はEagle MEM(日水製薬)に10%中胎児血清(Microbological Association,USA)を加えたものを,照射光源はアルゴン色素レ-ザ-光(ADL,630nm,SpectraーPhysics)およびUV(UVA;300ー430nm ...
60115251, 24592, 内藤, 克輔
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Selective Uptake of Hematoporphyrin Derivative into Human Cerebral Glioma [PDF]
The uptake of hematoporphyrin derivative (HpD) into human cerebral glioma was measured using a porphyrin extraction technique. Patients with cerebral glioma were injected with HpD at a dose of 5 mg/kg body weight 24 hours before surgery and ...
Stanley S. Stylli +5 more
core +1 more source
Stereotactic Intratumoral Photodynamic Therapy for Recurrent Malignant Brain Tumors [PDF]
Photodynamic therapy (PDT) using purified hematoporphyrin derivative and stereotactic intratumorally implanted optical laser fiber(s) was used to treat patients with recurrent malignant gliomas and metastatic melanoma of the brain.
Sharon S. Cush +3 more
core +1 more source
Contractile properties of isolated vascular smooth muscle after photoradiation [PDF]
The purpose of this study was to characterize the responses of various types of vascular smooth muscle to conditions that would be encountered during photodynamic therapy, namely laser illumination of photosensitizer-pretreated tissue.
J. L. Hart +4 more
core +1 more source
Destruction of rat mammary tumor and normal tissue microcirculation by hematoporphyrin derivative photoradiation observed in vivo in sandwich observation chambers [PDF]
The effect of hematoporphyrin derivative photoradiation on tumor and normal tissue microcirculation was studied microscopically in vivo on rats with mammary carcinomas transplanted into subcutis in transparent observation chambers.
Franken, K. A. +5 more
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