ヒト膀胱癌由来培養細胞株KKー47細胞よりHAT selectoonにて得られた細胞株は細胞感染が認められ,野性型細胞を用いて本研究を逐行した。光感受性物質はHpDI(Queen Elizabeths Hospital,Australia)を,培養液はEagle MEM(日水製薬)に10%中胎児血清(Microbological Association,USA)を加えたものを,照射光源はアルゴン色素レ-ザ-光(ADL,630nm,SpectraーPhysics)およびUV(UVA;300ー430nm ...
60115251, 24592, 内藤, 克輔
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Selective Uptake of Hematoporphyrin Derivative into Human Cerebral Glioma
The uptake of hematoporphyrin derivative (HpD) into human cerebral glioma was measured using a porphyrin extraction technique. Patients with cerebral glioma were injected with HpD at a dose of 5 mg/kg body weight 24 hours before surgery and ...
Stanley S. Stylli +5 more
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Stereotactic Intratumoral Photodynamic Therapy for Recurrent Malignant Brain Tumors
Photodynamic therapy (PDT) using purified hematoporphyrin derivative and stereotactic intratumorally implanted optical laser fiber(s) was used to treat patients with recurrent malignant gliomas and metastatic melanoma of the brain.
Sharon S. Cush +3 more
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Contractile properties of isolated vascular smooth muscle after photoradiation
The purpose of this study was to characterize the responses of various types of vascular smooth muscle to conditions that would be encountered during photodynamic therapy, namely laser illumination of photosensitizer-pretreated tissue.
J. L. Hart +4 more
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The effect of hematoporphyrin derivative photoradiation on tumor and normal tissue microcirculation was studied microscopically in vivo on rats with mammary carcinomas transplanted into subcutis in transparent observation chambers.
Franken, K. A. +5 more
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Studies of photochemical internalisation: mechanisms and strategies in cancer therapeutics
Photochemical internalisation (PCI) is a technique which enhances targeted drug delivery using light in combination with a photosensitiser. It is a modification of photodynamic therapy (PDT) which involves sub-lethal photodynamic treatment to modify ...
Wang, T.-W.
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Two Molecular Weights Holothurian Glycosaminoglycan and Hematoporphyrin Derivative-Photodynamic Therapy Inhibit Proliferation and Promote Apoptosis of Human Lung Adenocarcinoma Cells. [PDF]
Hao-Yu D +5 more
europepmc +1 more source
Advances in Management of Bladder Cancer-The Role of Photodynamic Therapy. [PDF]
Kubrak T +4 more
europepmc +1 more source
Photoinactivation and Photoablation of <i>Porphyromonas gingivalis</i>. [PDF]
Harris DM, Sulewski JG.
europepmc +1 more source
Modulation of Intratumoral Fusobacterium nucleatum to Enhance Sonodynamic Therapy for Colorectal Cancer with Reduced Phototoxic Skin Injury. [PDF]
Qu X +11 more
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