Results 31 to 40 of about 1,492 (143)

Synthesis, radiolabeling, biodistribution and fluorescent imaging of histidine-coupled hematoporphyrin

, 2012
Introduction: Hematoporphyrin (Hp) and hematoporphyrin derivatives (HpDs) have been widely used as photosensitizers in photodynamic therapy (PDT). Radiolabeling of HpDs is helpful for preclinical and clinical studies of PDT.
Chu, Taiwei, Liu, Fei, Bai, Jing, Shen, Bo, Zhang, Bin, Bao, Shanglian, Liu, Yupeng   +6 more
core   +1 more source

Elimination Pathway of Hematoporphyrin from Normal and Tumor-Bearing Rats

, 1982
Hematoporphyrin orally administered to rats largely precipitates in the stomach thus reaching the various tissues at a very slow rate. Whatever the administration pathway (oral, i.p., i.V.), hematoporphyrin is eliminated in the feces with no apparent ...
Fulvio Calzavara, Luigi Corti, Luigi Tomio, Benedetto Salvato, Pier Luigi Zorat, Giulio Jori, Elena Reddi   +6 more
core   +1 more source

Participation of Mast Cells and Complement in the Immediate Phase of Hematoporphyrin-Induced Phototoxicity [PDF]

, 1984
We have investigated the roles of mast cells and the complement system in the immediate phase of hematoporphyrin-induced phototoxicity in guinea pigs. Clinically, i.v.
Kamide, Ryoichi, Lim, Henry W, Gigli, Irma   +2 more
core   +1 more source

Two Molecular Weights Holothurian Glycosaminoglycan and Hematoporphyrin Derivative-Photodynamic Therapy Inhibit Proliferation and Promote Apoptosis of Human Lung Adenocarcinoma Cells. [PDF]

Integr Cancer Ther, 2023
Hao-Yu D, Ding-Yi Y, Bao-Hong X, Aihua S, Xiao-Qian D, Cun-Zhi L.   +5 more
europepmc   +1 more source

Time Dependence of Hematoporphyrin Distribution in Selected Tissues of Normal Rats and in Ascites Hepatoma

, 1979
The distribution of hematoporphyrin was determined in normal rats and in rats bearing ascites hepatoma as a function of time after i.p. injection of 10-20 mg/kg of dye. In both cases, hematoporphyrin displayed a high affinity for the tumor cells.
Fulvio Calzavara, Pierluigi Zorat, Luigi Tomio, Benedetto Salvato, Giulio Jori, Elena Reddi, Giambeppi Pizzi   +6 more
core   +1 more source

Stereotactic Intratumoral Photodynamic Therapy for Recurrent Malignant Brain Tumors

, 1991
Photodynamic therapy (PDT) using purified hematoporphyrin derivative and stereotactic intratumorally implanted optical laser fiber(s) was used to treat patients with recurrent malignant gliomas and metastatic melanoma of the brain.
Sharon S. Cush, Stephen K. Powers, Lester Kwock, Diana L. Walstad   +3 more
core   +1 more source

Switch from inhibition to activation of the mitochondrial permeability transition during hematoporphyrin-mediated photooxidative stress. Unmasking pore-regulating external thiols [PDF]

, 2009
We have studied the mitochondrial permeability transition pore (PTP) under oxidizing conditions with mitochondria-bound hematoporphyrin, which generates reactive oxygen species (mainly singlet oxygen, 1O2) upon UV/visible light-irradiation and promotes ...
NIKOLOV P, SILEIKYTE, JUSTINA, JORI G, Jori, Giulio, BERNARDI, PAOLO, Dabbeni-Sala, Federica, DABBENI SALA, FEDERICA, Ricchelli, Fernanda, TOGNON G, GOBBO S, RICCHELLI F., ZULIAN, ALESSANDRA, Nikolov, Peter, PETRONILLI V, Gobbo, Silvano, Tognon, Giuseppe, Petronilli, Valeria   +16 more
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Analysis of Hematoporphyrin as a synthesizer for Hematoporphyrin IX and Hematoporphyrin Dihydrochloride

, 2019
By Joseph Mccauley, Chemistry Advisor: Peng Zhang Presentation ID: CC_5 Abstract: Abstract Hematoporphyrin (HP) and hematoporphyrin IX (HPIX) have been successful in experimental usage as leading compounds in nanoparticle ...
Zhang, Peng, Mccauley, Joseph
core  

A Comparison of tumor demarcation potential for various hematoporphyrin derivatives and phtalocyanine using laser-induced fluorescence

, 1988
Laser-induced fluorescence data for rats injected with the different tumor-marking drugs, dihematoporphyrin ether, poly hematoporphyrin esters, hematoporphyrin and phtalocyanine, are presented.
S Andersson-Engels, Andersson-Engels, S., K Svanberg, Johansson, J., Ankerst, J., Svanberg, K.,, Svanberg, K., Andersson-Engels, S.,, S Svanberg, Svanberg, S.,, Svanberg, S., Ankerst, J.,, Lund University., J Ankerst, J Johansson   +14 more
core   +1 more source

Advances in Management of Bladder Cancer-The Role of Photodynamic Therapy. [PDF]

Molecules, 2022
Kubrak T, Karakuła M, Czop M, Kawczyk-Krupka A, Aebisher D.   +4 more
europepmc   +1 more source