Catalytic Amyloids: Turning Fibrils Into Biocatalysts
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito +3 more
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Dietary nitrosyl-heme from processed meats and its association with colorectal cancer risk: findings from the EPIC cohort study. [PDF]
Rizzolo-Brime L +26 more
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Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris +2 more
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Human Protein Z as the Second Known Heme-Binding Protein from the Endogenous Blood Coagulation Inhibitor System. [PDF]
Lindemann P, Hopp MT.
europepmc +1 more source
Diversity and conservation of interactions for binding heme in b-type heme proteins [PDF]
Marles-Wright, Jon +3 more
core +1 more source
The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications
Raman Deep Singh +8 more
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Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
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Heme Modulates Bladder Contractility Through the HO-CO-sGC-cGMP Pathway: Insights into Sickle Cell Disease-Associated Bladder Dysfunction. [PDF]
Pereira DA, Costa FF, Silva FH.
europepmc +1 more source
Bioavailability of Heme Iron in Biscuit Filling Using Piglets as an Animal Model for Humans
Guillermina Gonz lez-Rosendo Adri n Guillermo Quintero-Guti rrez
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Increased calcification by erythrophagocytosis in aortic valvular interstitial cells
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin +3 more
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