Results 261 to 270 of about 414,309 (352)

Reappraising heme oxygenase-1 as a ferroptosis modulator in atherosclerosis: a mechanism-focused review. [PDF]

Front Immunol
Xu J, Chen C, Yuan HY, Zhang YY, Wang CR, Xi X, Pan H, Li DH, Lu Y.   +8 more
europepmc   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Uncovering the structural impact of KatG Ser315 mutations in Mycobacterium tuberculosis via cryo-EM. [PDF]

Protein Sci
Allport T, Chaplin AK.
europepmc   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Biosensors for Detection of Labile Heme in Biological Samples. [PDF]

Biosensors (Basel)
Dobill K, Lechardeur D, Vidic J.
europepmc   +1 more source

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

Environmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir, Nihal Turkmen Alemdar, Esin Yulug, Ali Kulaber, Elif Ayazoglu Demir, Nadire Sevdenur Erdogan, Ahmet Mentese, Yuksel Aliyazicioglu   +7 more
wiley   +1 more source

Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in <i>Caenorhabditis elegans,</i> challenges a proposed role in heme trafficking. [PDF]

Elife
Sandkuhler SE, Youngs KS, Gottipalli O, Owlett LD, Bandora MB, Naaz A, Kim E, Wang L, Wojtovich A, Gupta V, Sacher M, Mackenzie SJ.   +11 more
europepmc   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

A reversible feedback mechanism regulating mitochondrial heme synthesis. [PDF]

J Biol Chem
Chitrakar I, Roberson AB, Ayres-Galhardo PH, Brown BL.   +3 more
europepmc   +1 more source

Optimized bacterial expression of a synthetic BRIL antibody

Acta Crystallographica Section F, EarlyView.
Here, we document the generation of a T7 Express ΔcybC strain allowing contaminant‐free expression of the anti‐BRIL Fab BAG2. We also report the crystal structure of BAG2 in complex with native cytochrome b562, a complex arising from expression in canonical Escherichia coli strains.The use of monoclonal fragments antigen binding (Fabs) is a prevalent ...
Benjamin F. Cooper, Georgia L. Isom
wiley   +1 more source