Results 271 to 280 of about 414,309 (352)

RETRACTION: Involvement of Heme Oxygenase-1 Induction in the Cytoprotective and Immunomodulatory Activities of <i>Viola patrinii</i> in Murine Hippocampal and Microglia Cells. [PDF]

Evid Based Complement Alternat Med
And Alternative Medicine EC.
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Pediatric Versus Adult Shear‐Induced Hemolysis—Are Age‐Related Blood Properties the Main Cause for Differences?

Artificial Organs, EarlyView.
Graphical summary of the experimental comparison of shear‐induced hemolysis in pediatric and adult blood using a Couette shearing device. Pediatric blood shows a trend toward lower increase in hemolysis at higher shear stress amplitudes, while no relevant differences are observed at low and intermediate stresses.
Vera Froese, Meike Fahrenholz, Ulrich Kertzscher, Michael Lommel, Maren Kleine‐Brueggeney   +4 more
wiley   +1 more source

Stage-Specific Proteomic Adaptations to Heme-Induced Oxidative Stress in Aedes aegypti: Differential Mechanisms in Larvae and Adults. [PDF]

Int J Mol Sci
Orozimbo KBDS, Bertonceli MAA, Silva RSB, Rodrigues RCC, Araújo JDS, Machado OLT, Almeida FA, Lemos FJA.   +7 more
europepmc   +1 more source

Monooxygenase Activity of Indoleamine 2,3-Dioxygenase. [PDF]

J Am Chem Soc
Lubis AB, Bailey AJ, Hanževački M, Williams C, Jesani M, González-Sánchez L, Arthur CJ, Wilson HC, Gallio AE, Moody PCE, Crump MP, Mulholland AJ, Orville AM, Clayden J, Raven EL.   +14 more
europepmc   +1 more source

Renal dysfunction in symptomatic Waldenström macroglobulinaemia: A nationwide Italian multicentre study

British Journal of Haematology, EarlyView.
Renal dysfunction represents a possible underrecognized complication of symptomatic WM; this condition correlates with adverse global and disease‐specific clinical outcomes. Summary The prognostic significance of impaired renal function in Waldenström macroglobulinaemia (WM) remains poorly defined.
Nicolò Danesin, Francesco Autore, Anna Maria Frustaci, Gianmarco Favrin, Emanuele Cencini, Alessandro Noto, Irene Dogliotti, Jacopo Olivieri, Marcello Riva, Isacco Ferrarini, Anna Maria Barbui, Sara Steffanoni, Dario Marino, Benedetta Puccini, Piero Maria Stefani, Rita Rizzi, Michele Merli, Angela Ferrari, Stefano Luminari, Carlo Visco, Livio Trentin, Andrea Visentin, Annarita Conconi, Simone Ferrero, Marzia Varettoni, Alessandra Tedeschi, Luca Laurenti, Francesco Piazza   +27 more
wiley   +1 more source

Iron and metabolic rewiring in cancer. [PDF]

Oncogenesis
Ciscar M, Rodríguez-Santana C, Santana-Codina N.   +2 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Development of a Cost-Effective, Heme-Tolerant Bovine Muscle Cell for Cultivated Meat Production. [PDF]

Foods
Oh YO, Yu CW, Cha MJ, Lee EJ, Kim P, Chang S.   +5 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source