The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons during rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic lipids and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production of ...
Rose Follis+2 more
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Flexibility and Hydration of the Q<sub>o</sub> Site Determine Multiple Pathways for Proton Transfer in Cytochrome <i>bc</i><sub>1</sub>. [PDF]
Camilo SRG, Arantes GM.
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Structural insights into allosteric inhibition of HRI kinase by heme binding via HDX-MS. [PDF]
Kanta S+4 more
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
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Comparison of Pyrazinamide with Isoniazid for Their Effects on the Heme Biosynthetic Pathway in Mouse Liver. [PDF]
Qin FY+6 more
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Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka+5 more
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Evidence for alcohol-mediated hemolysis and erythrophagocytosis. [PDF]
Zheng C+19 more
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Abstract Background Hormone pre‐treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. Objectives To evaluate whether hormone pre‐treatment with gonadotropin‐releasing hormone (GnRH) agonists or progestogens could improve fertility in women with ...
Gaetano Riemma+8 more
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Integrating Bulk and Single-Cell Transcriptomics with Machine Learning Reveals a Heme Metabolism-Based Panel for Lung Adenocarcinoma Chemotherapy Resistance. [PDF]
Zhao L+8 more
europepmc +1 more source