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Heme as activator and target for artemisinin: Towards multiple pharmacological bioactivity. [PDF]
Zhu P, Sun X, Fang Y, Li Y, Guo L.
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Synthetic Fe/Cu Complexes: Toward Understanding Heme-Copper Oxidase Structure and Function
Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial respiratory electron transport chain, which utilize a unique heterobinuclear active site to catalyze the 4H+/4e- reduction of dioxygen to water.
Gayan B Wijeratne +2 more
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Heme: emergent roles of heme in signal transduction, functional regulation and as catalytic centres
Chemical Society Reviews, 2019Protoporphyrin IX iron complex (heme) is an important cofactor for oxygen transfer, oxygen storage, oxygen activation, and electron transfer when bound to the heme proteins hemoglobin, myoglobin, cytochrome P450 and cytochrome c, respectively.
Toru Shimizu +2 more
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