Results 21 to 30 of about 137,322 (324)
Heme oxygenase-1, oxidation, inflammation and atherosclerosis [PDF]
Frontiers in Pharmacology, 2012 Atherosclerosis is an inflammatory process of the vascular wall characterized by the infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low density lipoproteins and induction of oxidative stress play a major role in ...
Jesus A Araujo, Min eZhang, Fen eYin
doaj +3 more sources
HEME OXYGENASE-1 AND FATTY LIVER DISEASE. [PDF]
Euromediterranean Biomedical Journal, 2016 Fatty liver diseases are a spectrum of liver pathologies characterized by abnormal hepatocellular accumulations of lipids. This condition may occur in both adults and children, particularly those who are obese or have insulin resistance or following ...
Daniela Nicolosi
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Heme oxygenase-1: potential therapeutic targets for periodontitis [PDF]
PeerJPeriodontitis is one of the most prevalent inflammatory disease worldwide, which affects 11% of the global population and is a major cause of tooth loss.
Weiwei Lv +9 more
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Heme oxygenase-1 protects cells from replication stress [PDF]
Redox BiologyHeme oxygenase-1 (HO-1, HMOX1) degrades heme protecting cells from heme-induced oxidative damage. Beyond its well-established cellular functions, heme has emerged as a stabilizer of G-quadruplexes.
Patryk Chudy +17 more
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Antioxidants, 2022 The heme oxygenase (HO) enzyme system catabolizes heme to carbon monoxide (CO), ferrous iron, and biliverdin-IXα (BV), which is reduced to bilirubin-IXα (BR) by biliverdin reductase (BVR).
S. Ryter
semanticscholar +1 more source
Heme Oxygenase-1 Signaling and Redox Homeostasis in Physiopathological Conditions
Biomolecules, 2021 Heme-oxygenase is the enzyme responsible for degradation of endogenous iron protoporphyirin heme; it catalyzes the reaction’s rate-limiting step, resulting in the release of carbon monoxide (CO), ferrous ions, and biliverdin (BV), which is successively ...
Valeria Consoli +3 more
semanticscholar +1 more source
Endoplasmic reticulum anchored heme-oxygenase 1 faces the cytosol
Haematologica, 2012 Heme-oxygenase 1 is an endoplasmic reticulum-anchored enzyme that breaks down heme into iron, carbon monoxide and biliverdin. Heme is a hydrophobic co-factor in many proteins, including hemoglobin.
Yehonatan Gottlieb +4 more
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Frontiers in Cellular Neuroscience, 2020 Subarachnoid hemorrhage is a specific, life-threatening form of hemorrhagic stroke linked to high morbidity and mortality. It has been found that the choroid plexus of the brain ventricles forming the blood-cerebrospinal fluid barrier plays an important ...
Peter Solár +10 more
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Gynecology Obstetrics & Reproductive Medicine, 2022 OBJECTIVE: To examine early pregnancy levels of serum heme oxygenase-1, soluble vascular endothelial growth factor receptor-1, B-cell lymphoma/leukemia-2 in relation to unfavorable pregnancy outcomes, including preeclampsia, fetal growth restriction ...
Havva Sutcu +4 more
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Frontiers in Immunology, 2020 Heme oxygenase (HO) is the primary antioxidant enzyme involved in heme group degradation. A variety of stimuli triggers the expression of the inducible HO-1 isoform, which is modulated by its substrate and cellular stressors.
S. C. Funes +7 more
semanticscholar +1 more source