Results 81 to 90 of about 126,441 (164)
Nrf2, a Cap’n’Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene*
Journal of Biological Chemistry, 1999 Stress response elements, which mediate induction of the mouse heme oxygenase-1 (HO-1) gene by several agents, resemble the binding site for the activator protein-1 (Jun/Fos), Maf, and Cap’n’Collar/basic leucine zipper (CNC-bZIP) families of proteins. In
J. Alam +5 more
semanticscholar +1 more source
Identification, heterologous expression and characterization of a dye-decolorizing peroxidase of Pleurotus sapidus [PDF]
, 2017 The coding sequence of a peroxidase from the secretome of Pleurotus sapidus was cloned from a cDNA library. Bioinformatic analyses revealed an open reading frame of 1551 bp corresponding to a primary translation product of 516 amino acids.
Lauber, Christiane +5 more
core +2 more sources
ATF4-dependent induction of heme oxygenase 1 prevents anoikis and promotes metastasis.
Journal of Clinical Investigation, 2015 The integrated stress response (ISR) is a critical mediator of cancer cell survival, and targeting the ISR inhibits tumor progression. Here, we have shown that activating transcription factor 4 (ATF4), a master transcriptional effector of the ISR ...
Souvik Dey +11 more
semanticscholar +1 more source
Deep Kinship Verification via Appearance-shape Joint Prediction and Adaptation-based Approach [PDF]
arXiv, 2019 Kinship verification aims to identify the kin relation between two given face images. It is a very challenging problem due to the lack of training data and facial similarity variations between kinship pairs. In this work, we build a novel appearance and shape based deep learning pipeline.
arxiv
Heme oxygenase-1: emerging target of cancer therapy
Journal of Biomedical Sciences, 2015 Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in mammalian cells.
L. Chau
semanticscholar +1 more source
Simulation of Heme using DFT+U: a step toward accurate spin-state energetics [PDF]
arXiv, 2007 We investigate the DFT+U approach as a viable solution to describe the low-lying states of ligated and unligated iron heme complexes. Besides their central role in organometallic chemistry, these compounds represent a paradigmatic case where LDA, GGA, and common hybrid functionals fail to reproduce the experimental magnetic splittings.
arxiv
PLoS ONE, 2015 A large group of flavonoids found in fruits and vegetables have been suggested to elicit health benefits due mainly to their anti-oxidative and anti-inflammatory properties.
G. Sun +6 more
semanticscholar +1 more source
Investigating electron conductivity regimes in the bacterial cytochrome wire OmcS [PDF]
arXivThe anaerobic bacterium \textit{Geobacter sulfurreducens} produces extracellular, electronically conductive cytochrome polymer wires that are conductive over micron length scales. Structure models from cryo-electron microscopy data show OmcS wires form a linear chain of hemes along the protein wire axis, which is proposed as the structural basis ...
arxiv
Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1.
Journal of Clinical Investigation, 2015 Subarachnoid hemorrhage (SAH) carries a 50% mortality rate. The extravasated erythrocytes that surround the brain contain heme, which, when released from damaged red blood cells, functions as a potent danger molecule that induces sterile tissue injury ...
N. Schallner +8 more
semanticscholar +1 more source
Role of Heme Oxygenase-1 in Murine Renal Allograft Acceptance [PDF]
, 2006 The acceptance of renal grafts in mice seems to be strain specific. While a kidney transplant between MHC disparate Balb/C and C57/B6 mice is rapidly rejected, a DBA kidney transplanted into a B6 mouse is spontaneously accepted and the acceptance is ...
Sass, Christina
core +1 more source