Designing Enzymatic Reactivity with an Expanded Palette
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley +1 more source
NADPH-Independent Fluorescent Probe for Live-Cell Imaging of Heme Oxygenase-1. [PDF]
Li L+7 more
europepmc +1 more source
Decreased Oxygen Toxicity in Mice Lacking Heme Oxygenase-1; Role of Iron• 1641 [PDF]
Phyllis A. Dennery+3 more
openalex +1 more source
Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation.
S. Ryter, A. Choi
semanticscholar +1 more source
An artificial enzymatic cascade to access natural vanillin from eugenol/clove oil was developed by revisiting the very first vanillin synthetic process from 19th century. The biosynthetic route consists of just two biocatalysts used as cell‐free preparation and molecular oxygen as oxidizing agent, outperforming also the natural microbial pathway which ...
Elisa Lanfranchi+12 more
wiley +1 more source
Heme Regulatory Motif of Heme Oxygenase-2 Is Involved in the Interaction with NADPH-Cytochrome P450 Reductase and Regulates Enzymatic Activity. [PDF]
Sugishima M+6 more
europepmc +1 more source
Heme oxygenase activity in prematures with Oxygen Radical Disease 59 [PDF]
I Németh+3 more
openalex +1 more source
Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren+15 more
wiley +1 more source
Heme oxygenase 1 confers gilteritinib resistance in FLT3-ITD acute myeloid leukemia in a STAT6-dependent manner. [PDF]
Zhang T+11 more
europepmc +1 more source