Results 221 to 230 of about 188,137 (274)

Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase

Proceedings of the National Academy of Sciences of the United States of America, 2014
M. Sugishima, Hideaki Sato, Y. Higashimoto, J. Harada, K. Wada, K. Fukuyama, M. Noguchi   +6 more
semanticscholar   +1 more source

INDUCTION OF HEME OXYGENASE BY COBALT-PROTOPORPHYRIN (COPP) IN SMALL BOWEL DONORS RESULTS IN DECREASE OF PRESERVATION/REPERFUSION INJURY AND IMPROVED ISOGRAFT SURVIVAL

, 1999
Elizabeth C. Squiers, Roland Buelow, Frank S. Szmalc, Suhasini Iyer, David Bruch, Diane G. Tice   +5 more
openalex   +1 more source

Forkhead Box O1 Promotes Osteogenic Differentiation of Periodontal Ligament Stem Cells in Hypoxia/Reoxygenation Environments by Regulating Heme Oxygenase-1 Scavenging of Reactive Oxygen Species. [PDF]

Int Dent J
Ye Y, Tang J, Ye J, Zhao B, Ma Y.
europepmc   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, Volume 182, Issue 16, Page 3695-3709, August 2025.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source

Heme oxygenase-1 modulates CD62E-dependent endothelial cell-monocyte interactions and mitigates HLA-I-induced transplant vasculopathy in mice. [PDF]

Front Immunol
Schuster L, Zaradzki M, Janssen H, Gallenstein N, Etheredge M, Hofmann I, Weigand MA, Immenschuh S, Larmann J.   +8 more
europepmc   +1 more source

Dauricine Overcomes Osimertinib Resistance in Lung Cancer by Inducing Ferroptosis via Stabilizing SAT1

Cancer Science, Volume 116, Issue 8, Page 2256-2269, August 2025.
Our study explores the potential of dauricine, a bioactive compound from Menispermum dauricum, to overcome osimertinib resistance in lung cancer. We demonstrate that dauricine, when combined with osimertinib, induces ferroptosis in resistant lung cancer cells by stabilizing SAT1, a key enzyme in oxidative stress regulation.
Biying Men, Zhijie Chen, Haotian Ge, Zhuoying Yang, Liang Yun, Jianjun Jiang, Meijuan Dian, Yujing He, Zehao Zhou, Ruihao Zhang, Tianbao Yan, Zichao Li, Yingxin Zhang, Yongjie He, Junming He, Xuguang Rao, Shuan Rao   +16 more
wiley   +1 more source

Heme oxygenase-1 and acute kidney injury

Current opinion in nephrology and hypertension, 2014
K. Nath
semanticscholar   +1 more source

INDUCTION OF HEME OXYGENASE AND NITRIC OXIDE SYNTHASE IN AN EXPERIMENTAL TUMOR IN RAT AND ITS IMPLICATION FOR TUMOR GROWTH

, 1997
Koichi Doi, Takaaki Akaike, Shin‐ichiro Fujii, Norisato Ikebe, Toru Beppu, Minetaro Ogawa, Shigeki Shibahara, Hiroshi Maeda   +7 more
openalex   +1 more source

Heme oxygenase, biliverdin reductase, and bilirubin pathways regulate oxidative stress and insulin resistance: a focus on diabetes and therapeutics. [PDF]

Clin Sci (Lond)
Lee WH, Kipp ZA, Pauss SN, Martinez GJ, Bates EA, Badmus OO, Stec DE, Hinds TD.   +7 more
europepmc   +1 more source

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

Cancer Science, Volume 116, Issue 8, Page 2125-2136, August 2025.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu, Xiaofeng Xiong, Mingyi Dong, Linfei Luo, Zixiang Huang, Kedong Xu, Lianwu Zhao, Fenfen Wang, Zhili Wen   +8 more
wiley   +1 more source