Results 231 to 240 of about 115,890 (298)

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Gnetum montanum extract attenuates lipopolysaccharide induced acute lung inflammation through Nrf2 and heme oxygenase 1 mediated redox modulation in macrophages. [PDF]

Sci Rep
Pham DV, Tran HL, Nguyen TH, Bui HN, Nguyen HN, Le TN, Pham TH, Nguyen TD.   +7 more
europepmc   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Heme Oxygenase-1 Expression as a Prognostic Marker in Early-Stage HCC Undergoing Resection or Liver Transplantation. [PDF]

Life (Basel)
Cadar R, Vasilescu AM, Trofin AM, Nastase AG, Zabara M, Muzica C, Ursulescu CL, Danciu M, Pascu A, Buzincu I, Ciobanu D, Victor I, Lupascu CD.   +12 more
europepmc   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Evaluation of saliva and serum heme oxygenase, arylesterase and nuclear factor erythroid 2-related factor 2 levels in patients with stage III periodontitis: a cross sectional study. [PDF]

Clin Oral Investig
Yildiz ZH, Ustaoğlu G, Avci E.
europepmc   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

MedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying, Huilin Wang, Xiu Lu, Wenjuan Zhang, Zhehao Lin, Kai Wang, Shangxuan Li, Lu Chen, Mingchao Jiang, Sarkawt Hamad, Yi Wang, Jianmin Wu, Shukuan Ling   +12 more
wiley   +1 more source

An oral heme oxygenase inhibitor targets immunosuppressive perivascular macrophages in preclinical models of cancer. [PDF]

Sci Transl Med
Bahri M, Al-Adhami T, Demirel E, Sarkar J, Feehan KT, Anstee JE, Cheung TS, Sosnowska D, Woodman CA, Macmorland W, Yang DD, Rosekilly J, Gitsaki-Taylor R, Gillett CE, Scudamore CL, Spicer J, Rahman KM, Arnold JN.   +17 more
europepmc   +1 more source