Results 251 to 260 of about 146,694 (331)

Heme oxygenase-1 protects cells from replication stress. [PDF]

open access: yesRedox Biol
Chudy P   +17 more
europepmc   +1 more source

Oxidative Stress in Antigen Processing and Presentation

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang   +9 more
wiley   +1 more source

Burdock Fructooligosaccharide Protects Against Diabetic Nephropathy in Mice by Regulating Nrf2 Signaling

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
In short, this study found that BFO could protect DN mice against renal injury induced by a high‐fat diet combined with STZ. Its protective effect may depend on the Nrf2/HO‐1 signaling pathway. ABSTRACT Diabetic nephropathy (DN) is a common complication of diabetes mellitus, with oxidative stress playing a critical role in its development.
Lei Zhu   +10 more
wiley   +1 more source

Heme oxygenase-1 and anti-inflammatory M2 macrophages.

open access: yesArchives of Biochemistry and Biophysics, 2014
Y. Naito, T. Takagi, Yasuki Higashimura
semanticscholar   +1 more source

Colo‐Protective Effects of Pentoxifylline Alone or in Combination With Mesalamine in Colitis Through Sphingosine Kinase 1/Sphingosine 1 Phosphate, and Zonula Occuldin 1 Pathways: New Molecular Approach

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Multiple signaling pathways have been implicated in the pathogenesis of ulcerative colitis (UC), including Sphingosine Kinase 1 (SPHK)/Sphingosine‐1‐Phosphate (S1P), AMP‐activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)/NLR family pyrin domain‐containing 3 (NLRP3), zonula occludens‐1 (ZO‐1), and signal transducer and ...
Fatemah A. Alherz   +18 more
wiley   +1 more source

Structural Engineering of Sonosensitive Nanohybrids by Active Vanadium Species toward Collapse of Multi‐Antioxidant Defenses and Boosted Therapy of Triple‐Negative Breast Cancer

open access: yesSmall Structures, Volume 6, Issue 6, June 2025.
A sonosensitive nanohybrid with defect structures is constructed through in situ etching deposition of vanadyl phosphate onto porphyrin metal–organic frameworks (MOFs), in which defects induce narrower bandgap and serve as charge traps for enhancing singlet oxygen generation under ultrasound irradiation. Additionally, released vanadium species overcome
Tingting Zhang   +8 more
wiley   +1 more source

Peripheral human red blood cell development in human immune system mouse model with heme oxygenase-1 deficiency. [PDF]

open access: yesBlood Adv
Patel AK   +16 more
europepmc   +1 more source

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