Results 31 to 40 of about 22,924 (125)

Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure

open access: yesStem cell research & therapeutics, 2017
Mesenchymal stem cells (MSCs) have been studied for the treatment of acute liver failure (ALF) for several years. MSCs may exert their effect via complex paracrine mechanisms.
Zhi-heng Zhang   +6 more
semanticscholar   +1 more source

Heme Oxygenase-1: Clinical Relevance in Ischemic Stroke

open access: yesCurrent pharmaceutical design, 2018
Stroke is the second-leading cause of death and a leading cause of serious long-term disability worldwide, with an increasing global burden due to the growing and aging population.
D. Bereczki, J. Balla, D. Bereczki
semanticscholar   +1 more source

The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer

open access: yesJournal of Biological Chemistry, 2017
Mammals incorporate a major proportion of absorbed iron as heme, which is catabolized by the heme oxygenase 1 (HO1)–NADPH-cytochrome P450 reductase (CPR) complex into biliverdin, carbon monoxide, and ferrous iron.
I. Yanatori   +3 more
semanticscholar   +1 more source

Heme oxygenase-1 regulates mitochondrial quality control in the heart.

open access: yesJCI Insight, 2016
The cardioprotective inducible enzyme heme oxygenase-1 (HO-1) degrades prooxidant heme into equimolar quantities of carbon monoxide, biliverdin, and iron.
T. Hull   +11 more
semanticscholar   +1 more source

Characterization of a novel P53 target gene, Heme Oxygenase (decycling) 1 (HMOX1)

open access: yes, 2010
The p53 tumour suppressor protein plays a pivotal role in coordinating the cellular response to a range of environmental and intracellular stresses. Multiple stress signals that activate p53 include hypoxia, telomere erosion, oncogenes and DNA damage, which is the best studied of them all.
openaire   +1 more source

Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1979
G. Drummond, A. Kappas
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy