Results 21 to 30 of about 63,602 (67)

The Ferrous Verdoheme−Heme Oxygenase Complex is Six-Coordinate and Low-Spin

, 2016
A biosynthetic and enzymatic method was developed for the preparation of 13C-labeled verdoheme, which permits the 13C NMR spectroscopic characterization of this elusive intermediate in the heme oxidation path catalyzed by the enzyme heme oxygenase.
Christopher O. Damaso (2659240), Mario Rivera (1314483), Richard A. Bunce (630478), Mikhail V. Barybin (1483429), Angela Wilks (1923148)   +4 more
core   +1 more source

Pharmacological and Clinical Significance of Heme Oxygenase-1

, 2021
This Special Issue collates and updates the current knowledge of the pharmacology and clinical applications concerning the enzyme heme oxygenase (HO) [...
Nader G. Abraham, Abraham, Nader G, David E. Stec, Stec, David E   +3 more
core   +1 more source

Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cells

, 2008
Heme oxygenase, the rate controlling enzyme for heme catabolism, is inducible by a variety of treatments, some of which induce by a heme-dependent mechanism and others by a heme-independent mechanism.
Greene, Yvonne J., Healey, John F., Cable, Edward Earl, Bonkovsky, Herbert L., Evans, Chheng-Orn   +4 more
core   +1 more source

Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

, 2020
Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1
Ching-Feng Cheng, You-Chen Chao, Wen-Lin Su, Chih-Pei Lin, Ping-Sheng Wu, Hui-Ching Hang, Hang, Hui-Ching, Su, Wen-Lin, Wu, Ping-Sheng, Lin, Chih-Pei, Chao, You-Chen, Cheng, Ching-Feng   +11 more
core   +1 more source

Malaria and susceptibility to other infections [PDF]

Malaria is widely perceived as immunosuppressive. Despite extensive phenomenological description, the underlying mechanisms remain poorly described. The aim of this thesis was to identify possible mechanisms by which malaria modifies host defence, and
Cunnington, Aubrey Justin
core   +1 more source

Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme

, 2009
The effects of heme on the induction of mRNA and protein synthesis for heme oxygenase-1 have been studied in primary cultures of chick embryo liver cells.
Srivastava, Kishore K., Cable, Edward Earl, Bonkovsky, Herbert L., Donohue, Susan E.   +3 more
core   +1 more source

Maximum likelihood tree and schematic diagrams of heme oxygenase proteins.

, 2018
Maximum likelihood (ML) tree based on an alignment of 510 heme oxygenase amino acid sequences from 1,678 taxa. Red algal heme oxygenases had three isotypes of heme oxygenase; HMOX1, HMOX2, and pbsA.
Kyeong Mi Kim (5184491), Daryl W. Lam (5184494), Hwan Su Yoon (41567), Ji Won Choi (137354), Chung Hyun Cho (5184488)   +4 more
core   +1 more source

Immunolocalization of heme oxygenase-1 in periodontal diseases

, 2014
Context: Chronic periodontitis is an inflammatory condition of supporting tissues initiated by organisms in dental plaque. The reactive oxygen species and free radicals mediate connective tissue destruction in periodontitis.
Leena Dennis Joseph, G Gayathri, S Muthukumar, R Suresh   +3 more
core   +1 more source

Pharmacological Preconditioning with Simvastatin Protects Liver from Ischemia-Reperfusion Injury by Heme Oxygenase-1 Induction

, 2011
Background. The protective role of heme oxygenase-1 (HO-1) against liver ischemia-reperfusion (I/R) injury in models of hypoxic and remote preconditioning has been proved.
LAI, I-RUE;CHANG, KING-JEN;CHEN, CHAU-FONG, 賴逸儒;張金堅;陳朝峰   +1 more
core   +1 more source

Heme Oxygenase Activity Correlates with Serum Indices of Iron Homeostasis in Healthy Nonsmokers

, 2016
Heme oxygenase (HO) catalyzes the breakdown of heme to carbon monoxide, iron, and biliverdin. While the use of genetically altered animal models in investigation has established distinct associations between HO activity and systemic iron availability ...
Andrew J. Ghio, Dina M. Schreinemachers
core   +1 more source