Results 31 to 40 of about 60,863 (124)

Heme Oxygenase Activity Correlates with Serum Indices of Iron Homeostasis in Healthy Nonsmokers

, 2016
Heme oxygenase (HO) catalyzes the breakdown of heme to carbon monoxide, iron, and biliverdin. While the use of genetically altered animal models in investigation has established distinct associations between HO activity and systemic iron availability ...
Andrew J. Ghio, Dina M. Schreinemachers
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Guanosine has no effect on heme-oxygenase-2 protein expression in PC12 cells

, 2011
Copyright information:Taken from "Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP"Purinergic Signalling 2005;1(2):161-172.Published online Jan 2005PMCID:PMC2096532.
Shaun Hindley (82281), Shucui Jiang (82282), Christian Bau (82279), Renata Ciccarelli (82283), Michel P. Rathbone (82287), Francesco Caciagli (82284), Pamela J. Middlemiss (82280), Eva S. Werstiuk (82286), Patrizia DiIorio (82285)   +8 more
core   +1 more source

Immune-Related Functions of Heme Oxygenase-1

, 2023
Heme oxygenase (HO)-1 is a well-known cytoprotective enzyme due to its enzymatic action, which involves the catalysis of heme into anti-apoptotic and antioxidant molecules such as bilirubin, biliverdin and CO [...
Maria G. Detsika, Elias A. Lianos
core   +1 more source

Heme oxygenase-1 & 2 and their potential contribution in heme induced colorectal carcinogenesis

, 2022
Background: Literature suggests Heme oxygenase (HO) system to be a double-edged sword which can promote both cytoprotection as well as carcinogenicity.
Cheng, Tracie, Lam, Alfred King-Yin, Gopalan, Vinod, Islam, Farhadul, Macfarlane, Lilian, Hewage, Dinu, Aktar, Sharmin, Nanayakkara, Sachith, Gamage, Sujani MK, Lu, Cu Tai, Dissabandara, Lakal   +10 more
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Heme oxygenase-1, heme oxygenase-2 and biliverdin reductase in peripheral ganglia from rat, expression and plasticity

, 1999
The expression of inducible and constitutive heme oxygenase and biliverdin reductase was studied in normal and cultured peripheral ganglia from adult rats, using immunocytochemistry and in situ hybridization.
E. Elmér, M. Kanje, S. Magnusson, Magnusson, S, Ekstrom, J, P. Alm, J. Ekström, L. Ny, Elmer, Eskil, Kanje, Martin, Alm, Per, Ny, L   +11 more
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Crystal structure of rat heme oxygenase-1 in complex with heme [PDF]

, 2000
Heme oxygenase catalyzes the oxidative cleavage of protoheme to biliverdin, the first step of heme metabolism utilizing O2 and NADPH. We determined the crystal structures of rat heme oxygenase-1 (HO-1)–heme and selenomethionyl HO-1–heme complexes.
Sakamoto, Hiroshi, Yoshiaki Omata, Yoshimitsu Kakuta, Hiroshi Sakamoto, Kakuta, Yoshimitsu, Noguchi, Masato, Omata, Yoshiaki, Masato Noguchi, Masakazu Sugishima, Keiichi Fukuyama, Fukuyama, Keiichi, Sugishima, Masakazu   +11 more
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Evidence for heme oxygenase activity in a heme peroxidase.

, 2009
The heme peroxidase and heme oxygenase enzymes share a common heme prosthetic group but catalyze fundamentally different reactions, the first being H(2)O(2)-dependent oxidation of substrate using an oxidized Compound I intermediate, and the second O(2 ...
Pipirou, Z, Eaton, G, Metcalfe, CL, Gumiero, A, Raven, EL, Moody, PC, Mistry, S, Handa, S, Badyal, SK, Basran, J   +9 more
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Evidence for Heme Oxygenase Activity in a Heme Peroxidase

, 2016
The heme peroxidase and heme oxygenase enzymes share a common heme prosthetic group but catalyze fundamentally different reactions, the first being H2O2-dependent oxidation of substrate using an oxidized Compound I intermediate, and the second O2 ...
Clive L. Metcalfe (2163964), Andrea Gumiero (2163955), Jaswir Basran (1280517), Emma Lloyd Raven (1280520), Sandeep Handa (1280511), Zoi Pipirou (2369983), Graham Eaton (1280529), Sharad Mistry (2369980), Peter C. E. Moody (2163961), Sandip K. Badyal (2163952)   +9 more
core   +1 more source

Heme catabolism and heme oxygenase in neurodegenerative disease

, 2004
Heme oxygenase, the rate-limiting step in heme catabolism, appears to play an important role in a number of neurodegenerative disorders, such as Alzheimer disease.
Takeda, Atsushi, Itoyama, Yasuto, Zhu, Xiongwei, Perry, George, Smith, Mark A., Dwyer, Barney E., Kimpara, Teiko, Ávila, Jesús   +7 more
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Heme oxygenase substrates acutely lower blood pressure in hypertensive rats

, 1996
Heme oxygenase catalyzes the metabolism of heme to biliverdine, free iron, and carbon monoxide. The current study was designed to determine if treatment with the heme oxygenase substrates heme-L-arginate or heme-L-lysinate, to stimulate formation of ...
M. Lavesa, M. J. Scholer, R. A. Johnson, K. DeSeyn, A. Nasjletti   +4 more
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