Results 61 to 70 of about 3,386 (219)

Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis

Chemistry – A European Journal, Volume 30, Issue 43, August 1, 2024.
Porphyrin atropisomerism opens an entirely new toolbox, allowing for the precise design of a porphyrin's molecular shape. This review details how this phenomenon has been utilised across all fields of chemistry, focusing on molecular recognition, medicinal chemistry and catalysis.
Sophie Maguire, Grant Strachan, Karolis Norvaiša, Claire Donohoe, Lígia C. Gomes‐da‐Silva, Mathias O. Senge   +5 more
wiley   +1 more source

Genetically Tunable Enzymatic C‒H Amidation for Lactam Synthesis [PDF]

, 2019
A major challenge in carbon‒hydrogen (C‒H) bond functionalization is to have the catalyst control precisely where a reaction takes place. Here we report engineered cytochrome P450 enzymes that perform unprecedented enantioselective C‒H amidation ...
Arnold, Frances H., Cho, Inha, Jia, Zhi-Jun   +2 more
core  

The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3

Molecular Microbiology, Volume 122, Issue 1, Page 29-49, July 2024.
A new mechanism for Yhb1 (orange) heme‐dependent activation involves direct interaction with the cell‐surface heme transporter Str3 (blue) in the presence of exogenous heme (red). Upon exposure to nitric oxide (˙NO), the expression of yhb1+ is induced, as its promoter is liberated from Fep1 repression (violet).
Florie Lo Ying Ping, Tobias Vahsen, Ariane Brault, Raphaël Néré, Simon Labbé   +4 more
wiley   +1 more source

Fungal systems for lignocellulose deconstruction: From enzymatic mechanisms to hydrolysis optimization

GCB Bioenergy, Volume 16, Issue 5, May 2024.
Biomass contains complex sugars and aromatic polymers that have the potential to serve as sustainable alternatives to fossil fuels and chemicals. Fungi possess specialized enzyme systems capable of breaking down lignocellulose into fermentable building blocks. This review analyses recent advancements in intricate fungal decomposition toolkits, shedding
Fengyun Ren, Fan Wu, Xin Wu, Tongtong Bao, Yucheng Jie, Le Gao   +5 more
wiley   +1 more source

Three-pulse multiplex coherent anti-Stokes/Stokes Raman scattering (CARS/CSRS) microspectroscopy using a white-light laser source [PDF]

, 2013
We have developed a three-pulse non-degenerate multiplex coherent Raman microspectroscopic system using a white-light laser source. The fundamental output (1064 nm) of a Nd:YAG laser is used for the pump radiation with the white-light laser output (1100 ...
Bito Kotatsu, Couderc Vincent, Hamaguchi Hiro-o, Kano Hideaki, Leproux Philippe, Okuno Masanari, 加納 英明   +6 more
core   +1 more source

Cultivating the uncultured: Harnessing the “sandwich agar plate” approach to isolate heme‐dependent bacteria from marine sediment

mLife, Volume 3, Issue 1, Page 143-155, March 2024.
Abstract In the classical microbial isolation technique, the isolation process inevitably destroys all microbial interactions and thus makes it difficult to culture the many microorganisms that rely on these interactions for survival. In this study, we designed a simple coculture technique named the “sandwich agar plate method,” which maintains ...
Jing Zhang, Qi‐Yun Liang, Da‐Shuai Mu, Fengbai Lian, Ya Gong, Mengqi Ye, Guan‐Jun Chen, Yuqi Ye, Zong‐Jun Du   +8 more
wiley   +1 more source

Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy. [PDF]

, 2019
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary identification and complete resection of the tumor are essential for glioma removal during brain surgery.
Alfano, Robert R, Cheng, Gangge, Liu, Cheng-Hui, Shi, Lingyan, Wang, Kai, Wu, Binlin, Yu, Xinguang, Zhang, Chunyuan, Zhang, Lin, Zhao, Mingyue, Zhou, Yan, Zhu, Ke, Zong, Rui   +12 more
core   +1 more source

Significantly enhanced proteolytic activity of cyclen complexes by monoalkylation [PDF]

, 2016
A simple approach towards efficient artificial proteases based on the cyclen ligand is presented. We thus achieved an increase of the proteolytic activity of two orders of magnitude when compared to the unsubstituted cyclen complex.
Dernedde, Jens, Hormann, Jan, Kulak, Nora, Perera-Bobusch, Chrischani, Wedepohl, Stefanie, Weise, Christoph   +5 more
core   +1 more source

Ionization basis for activation of enzymes soluble in ionic liquids [PDF]

, 2016
BACKGROUND: The complex interactions between electrolytes and proteins have been studied for more than a century. However, understanding is not yet complete and does not provide a basis for predicting the activity of enzymes in ionic media.
Halling, Peter, He, Biyan, Ou, Guangnan
core   +1 more source

Supramolecular electrode assemblies for bioelectrochemistry [PDF]

, 2017
For more than three decades, the field of bioelectrochemistry has provided novel insights into the catalytic mechanisms of enzymes, the principles that govern biological electron transfer, and has elucidated the basic principles for bioelectrocatalytic ...
Armstrong, Armstrong, Bayachou, Becucci, Becucci, Brzozowska, de Groot, de Groot, Elouarzaki, Fedurco, Feifel, Feifel, Fournier, Gao, Gilardi, Glazier, Guidelli, Guo, Gutierrez-Sanchez, Gutiérrez-Sanz, Gutiérrez-Sanz, Guto, Heath, Heller, Hu, Hughes, Hwang, Iost, Jadhav, Jadhav, Jeuken, Kato, Kendall, Kirchhofer, Kothe, Lalaoui, Lalaoui, Lars J. C. Jeuken, Lee, Li, Lorena Cortez, Lu, Ludwig, Léger, Léger, Ma, McGillivray, Melin, Mersch, Meyer, Meyer, Milton, Nassar, Oughli, Pallarola, Pelster, Plumeré, Radu, Radu, Rudiger, Rusling, Rusling, Shan, Stieger, Stoll, Tapia, Theodoros Laftsoglou, Valincius, Wang, Wiebalck, Wulff, Xiao, Yang, Zhang, Zhou   +74 more
core   +1 more source