Red meat and colon cancer : should we become vegetarians, or can we make meat safer ? [PDF]
The effect of meat consumption on cancer risk is a controversial issue. However, recent meta-analyses show that high consumers of cured meats and red meat are at increased risk of colorectal cancer.
Corpet, Denis E.
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Interaction of antimalarial drugs with hemin
Hemin (ferriprotoporphyrin IX) is shown to form complexes with the chloroquine class of antimalarial drugs. The Soret band of hemin becomes optically active upon the addition of chiral drugs. Results on the hemin-induced quenching of the fluorescence of chloroquine are consistent with the formation of a 2:1 hemin:drug complex with a formation constant ...
Dorairajan Balasubramanian+2 more
openaire +3 more sources
Condition-Dependent Coordination and Peroxidase Activity of Hemin-Aβ Complexes
The peroxidase activity of hemin-peptide complexes remains a potential factor in oxidative damage relevant to neurodegeneration. Here, we present the effect of temperature, ionic strength, and pH relevant to pathophysiological conditions on the dynamic ...
Chiara Bacchella+9 more
doaj +1 more source
Roles of nanomagnetic beads on biosensing: From fabrication to application
Leveraging their intrinsic superparamagnetic properties and rapid magnetic responsiveness, functionalized nanomagnetic beads have emerged as pivotal platforms in advanced biosensing system. Through surface engineering and structural design, these magnetic nanoparticles demonstrate multi‐capabilities, such as sample separation, signal enhancement, and ...
Junjie Li+11 more
wiley +1 more source
The induction of heme oxygenase 1 decreases contractility in human internal thoracic artery and radial artery grafts [PDF]
ObjectiveSpasm remains a potential problem encountered during the use of arterial grafts in coronary artery bypass surgery. Heme oxygenase plays a role in the control of arterial vasoreactivity.
Achouh, Paul+8 more
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Influence of Cosolvents on the Pressure Stability of Human Serum Albumin
Human serum albumin is able to bind various hydrophobic substances and drugs. To investigate this interaction, the protein structure is analyzed using small‐angle X‐ray scattering under high hydrostatic pressure. The resulting radius of gyration (see picture) indicates that hydrophobic substances influence the pressure stability of HSA differently ...
Jaqueline Savelkouls+3 more
wiley +1 more source
Heme oxygenase-1 as a modulator of intestinal inflammation development and progression [PDF]
Indexación: Scopus.Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the heme group contained in several important proteins, such as hemoglobin, myoglobin, and cytochrome p450.
Alexis M. Kalergis+12 more
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The Comparison of Acetic Acid and Strontium Chloride Procedures for Extraction of Hemin
Background and objectives: Hemin is a porphyrin compound derived from hemoglobin, the precursor of other porphyrin hemoglobin derivatives and the raw material of Hematin.
A Alavi+4 more
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Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin+2 more
wiley +1 more source
Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]
Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
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