Results 31 to 40 of about 39,725 (289)

Sequence Effect on the Activity of DNAzyme with Covalently Attached Hemin and Their Potential Bioanalytical Application

open access: yesSensors, 2022
In this work we investigated the effect of a DNA oligonucleotide sequence on the activity of a DNAzyme with covalently attached hemin. For this purpose, we synthesized seven DNA-hemin conjugates.
Joanna Kosman   +4 more
doaj   +1 more source

Red Blood Cells Preconditioned with Hemin Are Less Permissive to Plasmodium Invasion In Vivo and In Vitro. [PDF]

open access: yesPLoS ONE, 2015
Malaria is a parasitic disease that causes severe hemolytic anemia in Plasmodium-infected hosts, which results in the release and accumulation of oxidized heme (hemin). Although hemin impairs the establishment of Plasmodium immunity in vitro and in vivo,
Véronique Gaudreault   +4 more
doaj   +1 more source

Hemin-Induced Death Models Hemorrhagic Stroke and Is a Variant of Classical Neuronal Ferroptosis

open access: yesJournal of Neuroscience, 2022
Ferroptosis is a caspase-independent, iron-dependent form of regulated necrosis extant in traumatic brain injury, Huntington disease, and hemorrhagic stroke.
M. Zille   +9 more
semanticscholar   +1 more source

Hemin-Caged Ferritin Acting as a Peroxidase-like Nanozyme for the Selective Detection of Tumor Cells

open access: yes, 2021
Nanozyme is a class of artificial materials that possess enzyme-like activities and can overcome limitations of natural enzymes. However, controllability of the active sites, uniformity of the particles, and dispersion in the physiological media are ...
Manman Liu (4446067)   +11 more
core   +1 more source

Regulatory effects of Hemin on prevention and rescue of salt stress in rapeseed (Brassica napus L.) seedlings

open access: yesBMC Plant Biology, 2023
Background Salt stress severely restricts rapeseed growth and productivity. Hemin can effectively alleviate salt stress in plants. However, the regulatory effect of Hemin on rapeseed in salt stress is unclear.
Hui-Min Zhao   +8 more
doaj   +1 more source

Hemin-Coated Nanoparticles as Drug Delivery Vehicles for Chemotherapeutic Agents in Cancer Therapy

open access: yes, 2023
Chemotherapy holds a prominent position in contemporary cancer treatment modalities; however, poor water solubility, rapid clearance, and unintended side effects remain significant challenges. To mitigate these issues, various nanoparticle-based delivery
Ahmad Amirshaghaghi (5855252)   +6 more
core   +1 more source

Binding and accumulation of hemin in Porphyromonas gingivalis are induced by hemin [PDF]

open access: yesInfection and Immunity, 1994
Although hemin is an essential nutrient for the black-pigmented oral bacterium Porphyromonas gingivalis, the mechanisms involved in hemin binding and uptake are poorly defined. In this study, we have examined the binding of hemin and Congo red (CR) to P. gingivalis whole cells and have defined the conditions for maximal binding.
C A, Genco, B M, Odusanya, G, Brown
openaire   +2 more sources

Zippered G-quadruplex/hemin DNAzyme: exceptional catalyst for universal bioanalytical applications

open access: yesNucleic Acids Research, 2021
G-quadruplex (G4)/hemin DNAzyme is promising horseradish peroxidase (HRP)-mimic candidate in the biological field. However, its relatively unsatisfactory catalytic capacity limits the potential applications.
Jia Li   +9 more
semanticscholar   +1 more source

Hemin-Functionalized Microfluidic Chip with Dual-Electric Signal Outputs for Accurate Determination of Uric Acid

open access: yes, 2022
Herein, we develop a hemin-functionalized microfluidic chip with dual-electric signal outputs for accurate determination of uric acid (UA). Hemin is designed as the catalyst, which could trigger a built-in reference signal.
Mei Yang (51996)   +8 more
core   +1 more source

Interaction of low-density lipoproteins of serum with hemin*†

open access: yesJournal of Lipid Research, 1962
The interaction of low-density lipoproteins of human serum with hemin and the nature of the oxidative denaturation of low-density lipoproteins of serum catalyzed by hemin was studied by means of spectrophotometric and ultracentrifugal analyses and by ...
Toshiro Nishida, Fred A. Kummerow
doaj   +1 more source

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