Results 11 to 20 of about 39,725 (289)

Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate

Data in Brief, 2017
In this article newly synthesized azide derivative of hemin and DNA-hemin conjugate are characterized. Hemin-azide was purified using HPLC and characterized using elemental analysis, IR and NMR. The DNA-hemin conjugate was obtained via click chemistry [1]
J. Kosman, A. Stanislawska, A. Gluszynska, B. Juskowiak   +3 more
doaj   +4 more sources

Self-assembled, hemin-functionalized peptide nanotubes: an innovative strategy for detecting glutathione and glucose molecules with peroxidase-like activity

Nano Convergence, 2023
Accurately detecting dynamic changes in bioactive small molecules in real-time is very challenging. In this study, a hemin-based peptide assembly was rationally designed for the colorimetric detection of active small molecules.
Qiuxia Tu, Jian Feng, Guangwei Feng
exaly   +2 more sources

Hemin enhances the cardioprotective effects of mesenchymal stem cell-derived exosomes against infarction via amelioration of cardiomyocyte senescence

Journal of Nanobiotechnology, 2021
Background Application of mesenchymal stem cell-derived exosomes (MSC-EXO) has emerged as a novel therapeutic strategy for myocardial infarction (MI).
Huifeng Zheng, Xiaoting Liang, Qian Han, Zhuang Shao, Yuxiao Zhang, Linli Shi, Yimei Hong, Weifeng Li, Cong Mai, Qingwen Mo, Qingling Fu, Xiaoxue Ma, Fang Lin, Mimi Li, Bei Hu, Xin Li, Yuelin Zhang   +16 more
doaj   +2 more sources

Comparison of Characteristics and DNAzyme Activity of G4–Hemin Conjugates Obtained via Two Hemin Attachment Methods

Molecules, 2018
Two conjugation methods using different linkers were applied for the investigation of the spectral characteristics and activity of G-quadruplex (G4)–hemin conjugates.
Joanna Kosman, Krzysztof Żukowski, Bernard Juskowiak   +2 more
doaj   +2 more sources

Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron [PDF]

Frontiers in Physiology, 2017
Hemin plays a key role in mediating secondary neuronal injury after intracerebral hemorrhage (ICH) and the cell toxicity of hemin is thought to be due to iron that is liberated when hemin is degraded.
Yu-Fu Zhou, Chao Zhang, Chao Zhang, Guang Yang, Zhong-Ming Qian, Meng-Wan Zhang, Meng-Wan Zhang, Juan Ma, Juan Ma, Fa-Li Zhang, Fa-Li Zhang, Ya Ke   +11 more
doaj   +2 more sources

The Porphyromonas gingivalis ferric uptake regulator orthologue binds hemin and regulates hemin-responsive biofilm development. [PDF]

PLoS ONE, 2014
Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingivalis biofilm formation is dependent on environmental heme for which P.
Catherine A Butler, Stuart G Dashper, Lianyi Zhang, Christine A Seers, Helen L Mitchell, Deanne V Catmull, Michelle D Glew, Jacqueline E Heath, Yan Tan, Hasnah S G Khan, Eric C Reynolds   +10 more
doaj   +2 more sources

Interactions of hemin, antimalarial drugs and hemin-antimalarial complexes with phospholipid monolayers [PDF]

Chemistry and Physics of Lipids, 1984
Hemin, antimalarial drugs and complexes formed between them, have demonstrable effects on biological membranes. Using the phospholipid monolayer model, we show that hemin intercalates into the membrane and increases its surface pressure, depending on the lipid composition and the initial surface pressure: negative surface charges and particularly ...
Ginsburg, H., Demel, R.A.
openaire   +4 more sources

RIP1 and RIP3 mediate hemin-induced cell death in HT22 hippocampal neuronal cells

Neuropsychiatric Disease and Treatment, 2018
Xingfen Su,1 Handong Wang,2 Yuanxiang Lin,1 Fuxiang Chen1 1Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, People’s Republic of China; 2Department of Neurosurgery, Jinling Hospital ...
Su X, Wang H, Lin Y, Chen F
doaj   +1 more source

Dual-Function Role of Phenolated Albumin in Hemin-Mediated Hydrogel Formation [PDF]

Gels
Enzymatically crosslinked hydrogels are important in biomedical applications. However, conventional horseradish peroxidase (HRP)-based systems are expensive, unstable, and potentially immunogenic.
Shinji Sakai, Yuki Kitatani, Maasa Shiba, Thotage Asanka Vishwanath, Kelum Chamara Manoj Lakmal Elvitigala, Wildan Mubarok, Kousuke Moriyama   +6 more
doaj   +2 more sources

Interaction of antimalarial drugs with hemin

Bioscience Reports, 1983
Hemin (ferriprotoporphyrin IX) is shown to form complexes with the chloroquine class of antimalarial drugs. The Soret band of hemin becomes optically active upon the addition of chiral drugs. Results on the hemin-induced quenching of the fluorescence of chloroquine are consistent with the formation of a 2:1 hemin:drug complex with a formation constant ...
B, Panijpan, C, Mohan Rao, D, Balasubramanian   +2 more
openaire   +3 more sources