Aura and Stroke: relationship and what we have learnt from preclinical models
The Journal of Headache and Pain, 2019 Background Population-based studies have highlighted a close relationship between migraine and stroke. Migraine, especially with aura, is a risk factor for both ischemic and hemorrhagic stroke.
Muge Yemisci +1 more
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Nature Communications, 2020 Mutations of α2-Na/K ATPase can cause familial hemiplegic migraine via unclear mechanisms. Here, the authors show that deletion of α2-Na/K ATPase in astrocytes results in gene expression and metabolic changes leading to cortical spreading depression and ...
Sarah E. Smith +17 more
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CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]
, 2002 Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
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Journal of Biochemical and Clinical Genetics, 2019 Background: Familial hemiplegic migraine (FHM) is a rare disorder presented commonly with coma, hyperthermia, and headache. FHM is usually associated with fully reversible motor weakness as a specific symptom of aura.
Waleed Altwaijri +3 more
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Sporadic hemiplegic migraine and epilepsy associated with CACNA1A gene mutation.
, 2010 Familial hemiplegic migraine (FHM) is a clinically and genetically heterogeneous disease most commonly linked to CACNA1A gene mutation. Epilepsy rarely occurs in FHM and is seen predominantly with specific CACNA1A gene mutations.
Sperling, Michael R +3 more
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Tryptophan depletion increases nausea, headache and photophobia in migraine sufferers [PDF]
, 2006 Sensitivity to light was investigated 5 and 8 h after consumption of an amino acid drink which contained L-tryptophan (balanced amino acid condition: 19 controls and 22 migraine sufferers) or which produced a short-term reduction in brain serotonin ...
Drummond, P.D.
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Moyamoya Disease and Hemiplegic Migraine
Pediatric Neurology Briefs, 1993 A 6-year-old girl presenting with a 6-month history of classical familial migraine, complicated by transitory hemiparesis and moyamoya disease diagnosed by MRI, is reported from the Kaiser Permanente Medical Center, Hayward, CA.
J Gordon Millichap
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Painful stimulation of the temple during optokinetic stimulation triggers migraine-like attacks in migraine sufferers [PDF]
, 2005 To determine whether motion sickness induced by optokinetic stimulation would trigger migraine-like attacks, 27 migraine sufferers and 23 controls attended the laboratory up to three times at intervals of at least 3 weeks.
Granston, A., Drummond, P.D.
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Joint Metabonomic and Instrumental Analysis for the Classification of Migraine Patients with 677-MTHFR Mutations [PDF]
, 2010 Migraine is a neurological disorder that correlates with an increased risk of cerebrovascular lesions. Genetic mutations of the MTHFR gene are correlated to migraine and to the increased risk of artery pathologies.
LIBONI W +16 more
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Involvement of kainate glutamate receptors in the modulation of neuronal transmission in brain areas involved in migraine pathophysiology [PDF]
, 2009 Migraine pathophysiology is thought to involve activation of the trigeminal fibres which innervate dural structures. The nociceptive inflow from the meninges is relayed to the trigeminocervical complex (TCC), before ascending to higher brain areas ...
Andreou, A.
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