Results 141 to 150 of about 582 (156)
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Drug Research, 2017
AbstractThe main aim of the current study was to determine cardio-toxicity mechanisms of H. lepturus and protective effect of curcumin against this toxin in rats, using isolated heart mitochondria and cardiomyocytes. Our findings indicated that H. lepturus venom caused significantly ((P<0.05) cytotoxicity and caspase 3 activation in cardiomyocytes ...
Parvaneh, Naserzadeh +5 more
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AbstractThe main aim of the current study was to determine cardio-toxicity mechanisms of H. lepturus and protective effect of curcumin against this toxin in rats, using isolated heart mitochondria and cardiomyocytes. Our findings indicated that H. lepturus venom caused significantly ((P<0.05) cytotoxicity and caspase 3 activation in cardiomyocytes ...
Parvaneh, Naserzadeh +5 more
openaire +2 more sources
Journal of Current Toxicology and Venomics
Introduction: Venom allergens have been identified in the venom of scorpion, snake, bee, wasp, etc. Some allergy reactions in humans may refer to the venom allergens. Aim: Phylogenetic analysis of venom allergens from the transcriptome of Hemiscorpius lepturus scorpion was the main aim of the study.
Fatemeh Kazemi-Lomedasht +2 more
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Introduction: Venom allergens have been identified in the venom of scorpion, snake, bee, wasp, etc. Some allergy reactions in humans may refer to the venom allergens. Aim: Phylogenetic analysis of venom allergens from the transcriptome of Hemiscorpius lepturus scorpion was the main aim of the study.
Fatemeh Kazemi-Lomedasht +2 more
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Current Computer-Aided Drug Design
Background: Blocking Kv 1.2 and Kv 1.3 potassium channels using scorpion venom- derived toxins holds potential therapeutic value. These channels are implicated in autoimmune diseases such as neurodegenerative diseases, multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.
Maryam, Khalili-Salmasi +4 more
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Background: Blocking Kv 1.2 and Kv 1.3 potassium channels using scorpion venom- derived toxins holds potential therapeutic value. These channels are implicated in autoimmune diseases such as neurodegenerative diseases, multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.
Maryam, Khalili-Salmasi +4 more
openaire +2 more sources
Discovery of a New Analgesic Peptide, Leptucin, from the Iranian Scorpion, Hemiscorpius lepturus
Molecules, 2021Delavar Shahbazzadeh +2 more
exaly
Discovery of Leptulipin, a New Anticancer Protein from theIranian Scorpion, Hemiscorpius lepturus
Molecules, 2022Ali Rezaei +2 more
exaly
The Anti-cancer Effect of Two Extract Fractions from the Hemiscorpius lepturus Scorpion Venom
Applied Biochemistry and Microbiology, 2023Z. Setayesh-Mehr +2 more
openaire +1 more source