Results 151 to 160 of about 1,565 (185)
Some of the next articles are maybe not open access.
Hemoadsorption: Research Agenda and Potential Future Applications
2023After initial tentative steps with bioincompatible sorbents, hemoadsorption is making a comeback. This has been fueled by improved coating technology and improved sorbent technology. Both have markedly increased the safety, biocompatibility, and efficiency of hemoadsorption. Despite such development and an emerging body of evidence, the research agenda
Rinaldo Bellomo +2 more
openaire +2 more sources
The Use of Hemoadsorption in Cancer-Related Complications
Blood PurificationBackground: Patients with metastatic cancer are at risk of drug-related toxicity or disease-related complications leading to the development of organ failure such as rhabdomyolysis-associated acute kidney injury (AKI), liver failure, and multi-organ failure, often precipitated by endotoxinemia and sepsis. In cases of systemic hyperinflammatory response,
Premuzic, Vedran +2 more
openaire +3 more sources
The impact of hemoadsorption on antimicrobials
Journal of Translational Critical Care MedicineHemoadsorption (HA) is used for supportive blood purification therapy for conditions such as sepsis and immunological diseases. However, it may cause unintentional removal of antimicrobial drugs, potentially offsetting its therapeutic benefits. This review provides an overview of the impact of HA on the clearance of antimicrobials.
Taku Furukawa +2 more
openaire +1 more source
Hemoadsorption: One Name, Varied Techniques
Blood PurificationBackground: Despite significant efforts to improve outcomes for patients with sepsis and septic shock, mortality rates remain alarmingly high. Summary: Beyond standard management, novel adjuvant treatments seek to improve outcomes through a personalized approach.
Romagnoli, Stefano +3 more
openaire +3 more sources
Blood Purification
Introduction: Effective removal of protein-bound and middle/large molecular toxins is essential in maintenance hemodialysis (HD). This study compared the efficacy of high-flux HD combined with KHA130 hemoadsorption (HA) cartridge against hemodiafiltration (HDF) and high-flux HD combined with the HA130 HA cartridge.
Peng, Zhang +7 more
openaire +2 more sources
Introduction: Effective removal of protein-bound and middle/large molecular toxins is essential in maintenance hemodialysis (HD). This study compared the efficacy of high-flux HD combined with KHA130 hemoadsorption (HA) cartridge against hemodiafiltration (HDF) and high-flux HD combined with the HA130 HA cartridge.
Peng, Zhang +7 more
openaire +2 more sources
Removal of Psychotropic Drugs by Hemoadsorption with the HA380 Cartridge
Blood PurificationIntroduction: Psychotropic drug intoxication may require urgent management. Hemoadsorption (HA) may detoxify blood in such cases, but its effect has not been quantified. Methods: We studied in vivo removal of valproate, quetiapine, and escitalopram with HA using the Jafron HA380 cartridge in six sheep.
Taku Furukawa +8 more
openaire +3 more sources
Hemoadsorption in cardiac surgery with cardiopulmonary bypass
Journal of Translational Critical Care MedicinePost-pump syndrome (PPS) is a systemic inflammatory response that occasionally occurs after cardiac surgery with cardiopulmonary bypass (CPB), characterized by hemodynamic instability, organ dysfunction, and increased vascular permeability. PPS results from overlapping and redundant inflammatory responses triggered by the CPB and the surgical procedure
Céline Monard +7 more
openaire +2 more sources
Hemoadsorption/Hemodialysis: Rationale, Indications, and Practical Application
Uremic toxicity extends beyond small solutes to include middle molecules and protein-bound uremic toxins (PBUTs), which are inadequately removed by conventional dialysis. These limitations arise from membrane-dependent transport mechanisms and the high-affinity binding of PBUTs to albumin, restricting their effective clearance.Gonzalo Ramírez-Guerrero +3 more
openaire +2 more sources