Results 131 to 140 of about 49,325 (314)

Fatores precipitantes na porfiria cutânea tardia no Brasil com ênfase\ud nas mutações do gene (HFE) da hemocromatose. Estudo de 60 casos [PDF]

, 2013
BACKGROUND:\ud Porphyria cutanea tarda is the most common form of porphyria, characterized by the decreased activity of the uroporphyrinogen decarboxylase enzyme.
Abrantes-Lemos, Clarice Pires, Cançado, Eduardo Luiz Rachid, Nakhle, Maria Cristina, Reis, Vitor Manoel Silva dos, Vieira, Fatima Mendonça Jorge   +4 more
core   +1 more source

Neocyte‐enriched blood does not provide a survival advantage for red cells when compared to conventional filtered blood

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Red blood cell (RBC) concentrates are stored at 1–6°C for up to 42 days, but storage lesions can lead to wastage. Pooled neocytes may extend RBC shelf‐life, benefiting patients who require frequent transfusions. This study aimed to improve the longevity of stored RBCs by isolating neocytes and comparing the rate of ...
Adriaan Meyer, Heather Hendrickse, Glenda Mary Davison   +2 more
wiley   +1 more source

Addison′s disease

Contemporary Clinical Dentistry, 2012
Addison′s disease is a rare endocrinal disorder, with several oral and systemic manifestations. A variety of pathological processes may cause Addison′s disease.
Soumya Brata Sarkar, Subrata Sarkar, Supratim Ghosh, Subhankar Bandyopadhyay   +3 more
doaj   +1 more source

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding.

Proceedings of the National Academy of Sciences of the United States of America, 1998
We recently reported the positional cloning of a candidate gene for hereditary hemochromatosis called HFE. The gene product, a member of the major histocompatibility complex class I-like family, was found to have a mutation, Cys-282 --> Tyr (C282Y), in ...
J. Feder, D. Penny, A. Irrinki, V. K. Lee, J. Lebrón, N. Watson, Z. Tsuchihashi, E. Sigal, P. Bjorkman, R. Schatzman   +9 more
semanticscholar   +1 more source

In vitro quality of whole blood‐derived red cell concentrates collected, processed and stored in a blood bag set plasticized with di (2‐ethylhexyl) terephthalate

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Due to toxicity concerns, di(2‐ethylhexyl) phthalate (DEHP)—the most used plasticizer in polyvinyl chloride (PVC) whole blood (WB) collection and processing bag sets—will be effectively prohibited in medical devices in Europe from 2030. Removal of DEHP will primarily impact the in vitro quality of red blood cell (RBC)
Tatiana Stephenson, Anita Howell, Carly Olafson, Chryslain Sumian, Stefan Reichenberg, Quentin Brebant, Ken McTaggart, Geraldine M. Walsh   +7 more
wiley   +1 more source

Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment.

Gastroenterology, 2010
In the late 1800s, hemochromatosis was considered an odd autoptic finding. More than a century later, it was finally recognized as a hereditary, multi-organ disorder associated with a polymorphism that is common among white people: a 845G-->A change in ...
A. Pietrangelo
semanticscholar   +1 more source

Advances in the treatment of hepatocellular carcinoma: An overview of the current and evolving therapeutic landscape for clinicians

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is the sixth most common malignancy and the third leading cause of cancer‐related death worldwide. Contemporary advances in systemic and locoregional therapies have led to changes in peer‐reviewed guidelines regarding systemic therapy as well as the possibility of downstaging disease that may enable some patients
Dimitrios Moris, Alessandro Martinino, Sarah Schiltz, Peter J. Allen, Andrew Barbas, Debra Sudan, Lindsay King, Carl Berg, Charles Kim, Mustafa Bashir, Manisha Palta, Michael A. Morse, Michael E. Lidsky   +12 more
wiley   +1 more source

Assessment of metabolic dysfunction‐associated fatty liver disease in primary care: a consensus statement summary

Medical Journal of Australia, EarlyView.
Abstract Introduction Metabolic dysfunction‐associated fatty liver disease (MAFLD) is common. This evidence‐based consensus statement summary provides recommendations for the assessment and monitoring of adults with MAFLD in primary care. Main recommendations Adults with type 2 diabetes, obesity or two or more other metabolic risk factors should be ...
Leon A Adams, William W Kemp, Kate R Muller, Elizabeth E Powell, Stuart K Roberts, Luis Calzadilla Bertot, Stephanie Best, Gary Deed, Jon D Emery, Samantha L Hocking, Graham R Jones, John S Lubel, Sinead Sheils, Stephen M Twigg, Gerald F Watts, Jacob George   +15 more
wiley   +1 more source

IgG subclass levels in referred hemochromatosis probands with HFE p.C282Y/p.C282Y.

PLoS ONE
BackgroundIgG subclass levels in hemochromatosis are incompletely characterized.MethodsWe characterized IgG subclass levels of referred hemochromatosis probands with HFE p.C282Y/p.C282Y (rs1800562) and human leukocyte antigen (HLA)-A and -B typing ...
James C Barton, J Clayborn Barton, Luigi F Bertoli, Ronald T Acton   +3 more
doaj   +1 more source

PIGMENT FORMATION IN THE LIVER DURING AUTOLYSIS AND ITS RELATION TO THE PIGMENTATION OF HEMOCHROMATOSIS [PDF]

, 1912
Thomas P. Sprunt, H. S. Colwell, H. J. Hagan   +2 more
openalex   +1 more source