Results 151 to 160 of about 28,106 (200)
Some of the next articles are maybe not open access.
Clinica Chimica Acta, 2002
Hereditary hemochromatosis is the most common autosomal recessive disorder in populations of northern European descent.Many experts consider hemochromatosis to be an almost ideal disease for population screening because it essentially fulfills almost all the criteria for screening proposed by the WHO. However, others disagree and suggest that more data
McCullen, MA, Crawford, DHG, Hickman, PE
openaire +5 more sources
Hereditary hemochromatosis is the most common autosomal recessive disorder in populations of northern European descent.Many experts consider hemochromatosis to be an almost ideal disease for population screening because it essentially fulfills almost all the criteria for screening proposed by the WHO. However, others disagree and suggest that more data
McCullen, MA, Crawford, DHG, Hickman, PE
openaire +5 more sources
Blood, 2008
To the editor: In their recent article, Waalen et al[1][1] address an important question connected to screening programs for hemochromatosis: How to find the individuals that would benefit from treatment.
Arne, Asberg +3 more
openaire +2 more sources
To the editor: In their recent article, Waalen et al[1][1] address an important question connected to screening programs for hemochromatosis: How to find the individuals that would benefit from treatment.
Arne, Asberg +3 more
openaire +2 more sources
Current Treatment Options in Gastroenterology, 1999
The mainstay of treatment for hemochromatosis is therapeutic phlebotomy. The procedure is safe, effective, and relatively cheap. Deferoxamine (iron chelation) is necessary only in iron-loaded individuals who cannot undergo therapeutic phlebotomy. If therapy is initiated before complications develop, it is expected that no complications will ever ...
openaire +2 more sources
The mainstay of treatment for hemochromatosis is therapeutic phlebotomy. The procedure is safe, effective, and relatively cheap. Deferoxamine (iron chelation) is necessary only in iron-loaded individuals who cannot undergo therapeutic phlebotomy. If therapy is initiated before complications develop, it is expected that no complications will ever ...
openaire +2 more sources
2014
Hereditary hemochromatosis is due, in most cases, to a common genetic mutation in the HFE gene which leads to the C282Y substitution, which in turn can result in end organ damage from iron overload. The major manifestations in advanced disease are skin pigmentation, diabetes ('bronzed diabetes') and cirrhosis of the liver.
Wood, Marnie J. +2 more
openaire +4 more sources
Hereditary hemochromatosis is due, in most cases, to a common genetic mutation in the HFE gene which leads to the C282Y substitution, which in turn can result in end organ damage from iron overload. The major manifestations in advanced disease are skin pigmentation, diabetes ('bronzed diabetes') and cirrhosis of the liver.
Wood, Marnie J. +2 more
openaire +4 more sources
The Arthropathy of Hemochromatosis
Radiology, 1976Five cases of hemochromatosis arthropathy are presented and the distinctive radiological features of the disease are described. Although the condition is typically degenerative, showing subchondral cyst formation, sclerosis, and thinning of cartilage, its distribution is characteristic.
J H, Hirsch, F C, Killien, R H, Troupin
openaire +2 more sources
New England Journal of Medicine, 1993
In the United States the average daily intake of dietary iron ranges from 10 to 30 mg, but only about 1 mg is absorbed, to balance precisely the loss due to the sloughing of intact cells containing iron. Iron absorption can be increased if iron stores are depleted (usually through blood loss), and in genetically normal people absorption decreases with ...
Jane F. Desforges +2 more
openaire +2 more sources
In the United States the average daily intake of dietary iron ranges from 10 to 30 mg, but only about 1 mg is absorbed, to balance precisely the loss due to the sloughing of intact cells containing iron. Iron absorption can be increased if iron stores are depleted (usually through blood loss), and in genetically normal people absorption decreases with ...
Jane F. Desforges +2 more
openaire +2 more sources
Annals of Internal Medicine, 1998
The complications of iron overload in hemochromatosis can be avoided by early diagnosis and appropriate management.Therapeutic phlebotomy is used to remove excess iron and maintain low normal body ...
James C. Barton +7 more
openaire +1 more source
The complications of iron overload in hemochromatosis can be avoided by early diagnosis and appropriate management.Therapeutic phlebotomy is used to remove excess iron and maintain low normal body ...
James C. Barton +7 more
openaire +1 more source
2007
Iron is a major component of the Earth’s crust, but its own chemistry greatly limits utilization and also sets the basis for its toxicity. Hereditary hemochromatosis (HH) is the most common cause of iron overload in humans. For much of the twentieth century, HH was regarded as a monogenic disorder characterized by excess tissue deposits of iron ...
CORRADINI, Elena +2 more
openaire +2 more sources
Iron is a major component of the Earth’s crust, but its own chemistry greatly limits utilization and also sets the basis for its toxicity. Hereditary hemochromatosis (HH) is the most common cause of iron overload in humans. For much of the twentieth century, HH was regarded as a monogenic disorder characterized by excess tissue deposits of iron ...
CORRADINI, Elena +2 more
openaire +2 more sources
American Heart Journal, 1953
Abstract A case of hemochromatosis with death due to heart failure has been presented. The literature has been reviewed with respect to the pathophysiology of congestive heart failure due to hemochromatosis. The possibility of fatty degeneration of the heart as a precursor of myocardial fibrosis was discussed.
E B, LEVIN, A, GOLUM
openaire +2 more sources
Abstract A case of hemochromatosis with death due to heart failure has been presented. The literature has been reviewed with respect to the pathophysiology of congestive heart failure due to hemochromatosis. The possibility of fatty degeneration of the heart as a precursor of myocardial fibrosis was discussed.
E B, LEVIN, A, GOLUM
openaire +2 more sources
Seminars in Hematology, 2002
Juvenile hemochromatosis or type 2 hemochromatosis is a rare inherited recessive disease, which leads to severe iron overload earlier in life than HFE-related hemochromatosis. Increased transferrin saturation and serum ferritin as well as parenchymal iron deposition and liver fibrosis may be observed in childhood.
C. Camaschella +2 more
openaire +3 more sources
Juvenile hemochromatosis or type 2 hemochromatosis is a rare inherited recessive disease, which leads to severe iron overload earlier in life than HFE-related hemochromatosis. Increased transferrin saturation and serum ferritin as well as parenchymal iron deposition and liver fibrosis may be observed in childhood.
C. Camaschella +2 more
openaire +3 more sources