Reactive Oxygen Species in Unstimulated Hemocytes of the Pacific Oyster Crassostrea gigas: A Mitochondrial Involvement [PDF]
PLoS ONE, 2012 The Pacific oyster Crassostrea gigas is a sessile bivalve mollusc whose homeostasis relies, at least partially, upon cells circulating in hemolymph and referred to as hemocytes.
Aswani Volety +2 more
exaly +2 more sources
The Role of Mosquito Hemocytes in Viral Infections
Viruses, 2022 Insect hemocytes are the only immune cells that can mount a humoral and cellular immune response. Despite the critical involvement of hemocytes in immune responses against bacteria, fungi, and parasites in mosquitoes, our understanding of their antiviral
Chinmay V Tikhe +2 more
exaly +3 more sources
Transcriptomic characterization of mucosal hemocytes in the eastern oyster (Crassostrea virginica) underlines their potential role as immune sentinels [PDF]
Frontiers in ImmunologySubstantial progress has been made in understanding hemocytes within the hemolymph (herein referred to as circulatory hemocytes), which are essential for immune defense and various physiological functions in bivalve mollusks.
Sherif Abdallah +3 more
doaj +2 more sources
Single-Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans. [PDF]
Adv Sci (Weinh)Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Jin Y +6 more
europepmc +2 more sources
The Extracellular Matrix Proteins Pericardin and Lonely Heart Modulate the Directionality of Heart Contractions in Infected Mosquitoes. [PDF]
Arch Insect Biochem PhysiolPericardin and Lonely heart, which are components of the cardiac extracellular matrix, influence the direction in which the heart of mosquitoes propels hemolymph (blood). ABSTRACT The cardiac extracellular matrix provides structural support to the primary circulatory organ of an insect: a dorsal vessel that is divided into an aorta in the thorax and a ...
Ahmed S, Shah PK, Hillyer JF.
europepmc +2 more sources
Hallmarks of crustacean immune hemocytes at single-cell resolution
Frontiers in Immunology, 2023 In invertebrates, hemocytes are the key factors in innate immunity. However, the types of invertebrate immune hemocytes are unclassified due to the limitation of morphological classification.
Fan Xin +3 more
doaj +1 more source
Rapid regulation of hemocyte homeostasis in crayfish and its manipulation by viral infection
Fish and Shellfish Immunology Reports, 2021 In crustaceans, the number of circulating hemocytes changes rapidly in response to pathogen infection and injury, but the underlying mechanism remains unclear.
Zaichao ZHENG +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Immunocyte migration to infection sites is important for host cellular defense, but the main types of migrating hemocytes and their mechanisms against pathogen invasions are unclear in invertebrates. In the present study, a population of hemocytes in the
Zhao Lv +13 more
doaj +1 more source
NO Synthesis in Immune-Challenged Locust Hemocytes and Potential Signaling to the CNS
Insects, 2021 Similar to vertebrates, insects are exposed to a broad variety of pathogens. The innate insect immune system provides several response mechanisms such as phagocytosis, melanization, and the synthesis of antimicrobial or cytotoxic compounds. The cytotoxic
Stella Bergmann +4 more
doaj +1 more source
Frontiers in Immunology, 2021 DM9 refers to an uncharacterized protein domain that is originally discovered in Drosophila melanogaster. Two proteins with DM9 repeats have been recently identified from Pacific oyster Crassostrea gigas as mannose-specific binding pattern-recognition ...
Zhihao Jia +17 more
doaj +1 more source