Results 31 to 40 of about 10,891 (216)
ABSTRACT Dual inherited defects affecting urea cycle function are exceptionally rare. We report the first case, to our knowledge, of the coexistence of argininosuccinic aciduria (ASA) and citrin deficiency (CD). A girl born to consanguineous Tunisian parents presented at 6 months of age with recurrent seizures, vomiting, developmental delay, and severe
Mouna Zribi +6 more
wiley +1 more source
CLINICAL STUDIES OF HEMOFILTRATION -2- DISEQUILIBRIUM SYNDROME [PDF]
Hemofiltration and hemodialysis were compared with each other with respect to the percentage of onset of the disequilibrium syndrome. As a result, hemofiltration showed a lower frequency of onset, and the number of administrations of hypertensive agent ...
桑原, 守正 +3 more
core
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
The objective: to provide pathogenetic justification for the need for extracorporeal blood purification in the new coronavirus infection.Results: the article analyzes guidelines and the first experience of using extracorporeal methods in the new ...
A. A. Sokolov +4 more
doaj +1 more source
Sepsis: Epidemiology, Pathophysiology, and Management
Sepsis remains a major global health burden characterized by substantial geographical heterogeneity and a considerable disease burden in China. Its pathophysiology reflects an interconnected network involving excessive inflammation, oxidative stress, immune imbalance and immunoparalysis, mitochondrial damage, endothelial injury, gut dysbiosis ...
Guang‐Tao Pan +8 more
wiley +1 more source
Case series: Diquat poisoning with acute kidney failure, myocardial damage, and rhabdomyolysis
Diquat is a herbicide that can have deleterious effects on the kidneys, liver, heart, lungs, and central nervous system on ingestion. Diquat poisoning-associated rhabdomyolysis has rarely been reported.
Guangcai Yu +16 more
doaj +1 more source
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source
This prospective, single centre, observational study analysed the rate of catheter related blood stream infections in critically ill patients in intensive care units treated with haemo(dia)filtration. The infection rate was 3.8 per 1000 patient days.
C Forster, M Schönenberger, S Woodtli
doaj +1 more source
Safety and Feasibility of Magnetic Separation‐Based Blood Purification
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora +11 more
wiley +1 more source
Long-term Follow up in Chronic Hemofiltration
The course of treatment is demonstrated in 72 patients with chronic renal insufficiency who were undergoing regular hemofiltration for more than 6 months.
E. Quellhorst
core +1 more source

