Results 1 to 10 of about 35 (34)

Link Your Large Health Data Sets to the Area Deprivation Index, the ezADI Way

Research in Nursing &Health, Volume 48, Issue 3, Page 406-412, June 2025.
ABSTRACT Increasing attention has been paid to investigations on how social determinants of health (SDOH; e.g., income, employment, education, housing, etc.) impact health outcomes. However, these variables are often not collected in routine clinical practice.
Sunnie Reagan, Drew Prescott, Xueyuan Cao, Tyra Girdwood, Keesha Roach, Ansley Grimes Stanfill   +5 more
wiley   +1 more source

Impact of Food Insecurity on Malnutrition Treatment Response in Nigerian Children With Sickle Cell Anemia and Severe Acute Malnutrition

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background In this planned ancillary analysis of our completed clinical trial, we hypothesized that among older children with sickle cell anemia (SCA) and severe acute malnutrition, those with higher levels of food insecurity would have lower end‐of‐trial body mass index (BMI) z‐scores compared to their peers with SCA and lower levels of food ...
Gabriela Ramirez‐Cuebas, Shehu Umar Abdullahi, Safiya Gambo, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Garba Gwarzo, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +11 more
wiley   +1 more source

Depression Screening and Primary Care Engagement and Their Association With Socioeconomic Disadvantage Among Adolescents Aged 13–17 Years With Sickle Cell Disease

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT It is unclear if adolescents with sickle cell disease (SCD) are screened for depression, since primary care provider (PCP) visits decline with age and socioeconomic disadvantage may impact receipt of care. This 1‐year study identified 97% of adolescents with SCD at Nationwide Children's Hospital (NCH) had a PCP. Among those with an NCH PCP (n =
Anyssa Young, Joseph Stanek, Robert M. Cronin, Susan E. Creary   +3 more
wiley   +1 more source

Barriers to Care for Adults With Sickle Cell Disease: A Qualitative Descriptive Study

Health Expectations, Volume 28, Issue 3, June 2025.
ABSTRACT Objective We sought to understand barriers to care among adults with sickle cell disease (SCD) within our healthcare system. Study Setting and Design This qualitative descriptive study was conducted as part of a needs and assets assessment in preparation for the development of an adult sickle cell clinic.
Chanell Grismore, Lisa R. Roberts, Zephon D. Lister, Akshat Jain, Julio Silvestre, Ja'Nece Dickerson, Susanne B. Montgomery   +6 more
wiley   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

British Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue, Sophia K. Heuser, Marla Lindemann, Junjie Li, Masudur Rahman, Malte Kelm, Johannes Stegbauer, Miriam M. Cortese‐Krott   +7 more
wiley   +1 more source

The feasibility of pharmacokinetic‐based dosing of hydroxyurea for children with sickle cell anaemia in Uganda: Baseline results of the alternative dosing and prevention of transfusions trial

British Journal of Clinical Pharmacology, EarlyView.
Abstract Pharmacokinetic (PK)‐guided dosing of hydroxyurea for children with sickle cell anaemia (SCA) could optimize dosing and improve outcomes, but its feasibility has not been demonstrated in low‐resource settings where the majority of affected children live.
Alexandra Power‐Hays, Ruth Namazzi, Min Dong, Caroline Kazinga, Charles Kato, Sadat Aliwuya, Kathryn McElhinney, Andrea L. Conroy, Adam Lane, Chandy John, Alexander A. Vinks, Teresa Latham, Robert O. Opoka, Russell E. Ware   +13 more
wiley   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Treatment Experience Using a Micro‐Induction Buprenorphine Protocol for Chronic Pain in Pediatric Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with sickle cell disease (SCD) experience painful vaso‐occlusive episodes that increase with age; a subset develops chronic pain (CP). CP is usually managed with acute pain management guidelines despite evidence of ineffectiveness.
Ashwin Patel, Grace Kalmus, Carlton Dampier, Ifeyinwa Osunkwo, Tamara New, Beatrice Gee, Elna Saah   +6 more
wiley   +1 more source

Medication Utilization Among Children With Sickle Cell Disease in the United States

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Objective The medication management of children with sickle cell disease (SCD), especially since the release of the 2014 National Heart, Lung, and Blood Institute (NHLBI) SCD treatment guidelines, is not well described in the published literature.
Abiodun John Ologunowa, Kelly L. Matson, Jung Eun Lee, Meghan McCormick, Mary L. Greaney, Aisling R. Caffrey   +5 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source