Results 191 to 200 of about 204,284 (266)

Hydroxyurea (hydroxycarbamide) in haemoglobin SC disease: Moving from therapeutic hesitation to evidence‐guided care

open access: yesBritish Journal of Haematology, Volume 209, Issue 3, Page 1428-1430, September 2026.
Girard et al. report a retrospective, single‐centre, real‐world study evaluating hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease in Quebec. Hydroxyurea was associated with reduced vaso‐occlusive crisis composite events, mostly mild adverse events and no observed hyperviscosity‐related complications, while highlighting adherence
Tahereh Setayesh
wiley   +1 more source

The role of protein arginine methyltransferases in sickle cell‐mediated neurovascular impairments in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5586-5601, September 2026.
Background and Purpose Sickle cell disease (SCD) is a hereditary blood disorder caused by mutation of β‐globin. In SCD, haemoglobin polymerization causes red blood cells to assume a rigid sickle‐shape leading to neurovascular alterations, including development of vascular dementia – characterized by cognitive impairment and reduced cerebral perfusion ...
Julia Zaccarelli‐Magalhães   +11 more
wiley   +1 more source

Severe maternal morbidity according to sickle cell disease genotype. [PDF]

open access: yesPregnancy (Hoboken)
Kawakita T   +3 more
europepmc   +1 more source

Multidimensional Predictors of Disease Severity and Health Outcomes in Patients with Sickle Cell Disease: <i>A Data-Driven Clinical Insight</i>. [PDF]

open access: yesSaudi Med J
Alzahrani HA   +10 more
europepmc   +1 more source

Postoperative Complications in Patients With Sickle Cell Disease After Total Shoulder Arthroplasty. [PDF]

open access: yesJ Am Acad Orthop Surg Glob Res Rev
Zehner KM   +7 more
europepmc   +1 more source

Proximal tubulopathy in adult sickle cell disease: association of alpha-1 microglobulin. [PDF]

open access: yesClinics (Sao Paulo)
Engole YM   +11 more
europepmc   +1 more source

Hidden burdens: The dual burden of subclinical iron deficiency and hemoglobinopathies in afro-descendant populations of Colombia's Pacific coast: A public health concern. [PDF]

open access: yesJ Public Health Res
Marquez B Y   +7 more
europepmc   +1 more source

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