Girard et al. report a retrospective, single‐centre, real‐world study evaluating hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease in Quebec. Hydroxyurea was associated with reduced vaso‐occlusive crisis composite events, mostly mild adverse events and no observed hyperviscosity‐related complications, while highlighting adherence
Tahereh Setayesh
wiley +1 more source
Educational Case: Glucose-6-phosphate dehydrogenase (G6PD) deficiency anemia. [PDF]
Bussing K, Brehl N, Inman A, Davidson D.
europepmc +1 more source
Background and Purpose Sickle cell disease (SCD) is a hereditary blood disorder caused by mutation of β‐globin. In SCD, haemoglobin polymerization causes red blood cells to assume a rigid sickle‐shape leading to neurovascular alterations, including development of vascular dementia – characterized by cognitive impairment and reduced cerebral perfusion ...
Julia Zaccarelli‐Magalhães +11 more
wiley +1 more source
International flight-associated splenic infarction in a 33-year-old man with sickle cell trait. [PDF]
Chadelat A, Tassart M, Bachmeyer C.
europepmc +1 more source
Severe maternal morbidity according to sickle cell disease genotype. [PDF]
Kawakita T +3 more
europepmc +1 more source
Multidimensional Predictors of Disease Severity and Health Outcomes in Patients with Sickle Cell Disease: <i>A Data-Driven Clinical Insight</i>. [PDF]
Alzahrani HA +10 more
europepmc +1 more source
Postoperative Complications in Patients With Sickle Cell Disease After Total Shoulder Arthroplasty. [PDF]
Zehner KM +7 more
europepmc +1 more source
Proximal tubulopathy in adult sickle cell disease: association of alpha-1 microglobulin. [PDF]
Engole YM +11 more
europepmc +1 more source
Hidden burdens: The dual burden of subclinical iron deficiency and hemoglobinopathies in afro-descendant populations of Colombia's Pacific coast: A public health concern. [PDF]
Marquez B Y +7 more
europepmc +1 more source
GBT-1118 Rescued Impaired Bone Formation but Failed to Rescue Material Properties in Humanized Sickle-Cell-Disease Murine Model. [PDF]
Clarke K +5 more
europepmc +1 more source

