Results 211 to 220 of about 398,944 (237)

Hemoglobin SC Sickle Cell Disease Presenting as Acute Ischemic Stroke With Moyamoya Syndrome in an Adult: A Case Report. [PDF]

Cureus
Nidiginti T, Afzal B, Roy R, Baig F, Rai B.   +4 more
europepmc   +1 more source

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A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction

Science
Sickle cell disease (SCD) is a prevalent, life-threatening condition attributable to a heritable mutation in β-hemoglobin. Therapeutic induction of fetal hemoglobin (HbF) can ameliorate disease complications and has been intently pursued.
Pamela Y. Ting, Sneha Borikar, John Ryan Kerrigan, Noel M. Thomsen, Eamon Aghania, Amelia E Hinman, Alejandro Reyes, Nicolas Pizzato, Barna D. Fodor, Fabian Wu, M. Belew, Xiaohong Mao, Jian Wang, Shripad Chitnis, Wei Niu, Amanda Hachey, Jennifer S. Cobb, Nik Savage, Ashley Burke, Joshiawa Paulk, Dustin Dovala, James Lin, Matthew C. Clifton, Elizabeth Ornelas, Xiaolei Ma, Nathaniel F. Ware, Carina C. Sanchez, John Taraszka, Rémi Terranova, Judith Knehr, Marc Altorfer, S. W. Barnes, Rohan E. J. Beckwith, Jonathan M. Solomon, Natalie A Dales, Andrew W Patterson, Jürgen Wagner, T. Bouwmeester, Glenn Dranoff, Susan C. Stevenson, J. Bradner   +40 more
semanticscholar   +1 more source

Sickle Cell Disease: A Review.

Journal of the American Medical Association (JAMA), 2022
P. Kavanagh, Titilope A Fasipe, T. Wun
semanticscholar   +1 more source

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

Nature, 2021
Gregory A Newby, Jonathan S Yen, Kaitly J Woodard   +2 more
exaly  

The nephropathy of sickle cell trait and sickle cell disease

Nature Reviews Nephrology, 2022
Kenneth I Ataga, Santosh L Saraf, Vimal K Derebail   +2 more
exaly  

Malaria protection due to sickle haemoglobin depends on parasite genotype

Nature, 2021
Gavin Band, Ellen M Leffler, Carolyne M Ndila   +2 more
exaly  

Hemoglobin sickle‐lepore: Report of two siblings and review of the literature

American journal of hematology/oncology, 1993
D. Seward, R. Ware, T. Kinney
semanticscholar   +1 more source

Hemoglobin sickle D Punjab—a case report

, 2005
M. Mukherjee, R. Surve, R. Gangakhedkar, D. Mohanty, R. Colah   +4 more
semanticscholar   +1 more source

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Nature Biomedical Engineering, 2023
, Gregory A Newby, Rachel M Levine
exaly  

Clonal selection of hematopoietic stem cells after gene therapy for sickle cell disease

Nature Medicine, 2023
M Spencer Chapman, Jyoti Nangalia
exaly