Results 21 to 30 of about 35 (34)

Economic burden of sickle cell disease in Australia

Internal Medicine Journal, EarlyView.
Abstract Background Sickle cell disease (SCD) is an inherited condition that impairs red blood cell function, posing a substantial health burden on patients. As the prevalence of SCD in Australia rises due to migration, discussions surrounding treatment and management strategies are becoming more prominent. Aims Australia lacks a dedicated study on the
Steve Nwokeocha, Helen E. Haysom, Cameron Wellard, Tracy Roberts, Mwayi Kachapila, Melissa Chee, Dennis Petrie, Zoe K. McQuilten, Neil Waters, Anthea Greenway, Kylie Mason, Anna Nelson, Zane Kaplan, P. Joy Ho, Erica M. Wood, Adam Irving, on behalf of the Australian Haemoglobinopathy Registry   +16 more
wiley   +1 more source

Osteohistological analysis of metatarsals reveals new information on pathology and life history of troodontids from the Campanian Dinosaur Park Formation, Alberta, Canada

Journal of Anatomy, EarlyView.
A histological survey of troodontid metatarsals from the Dinosaur Park Formation (DPF) was conducted, revealing correlates for stresses in the troodontid arctometatarsus and providing the first histological assessment of pathologies for this taxon.
Christiana W. Garros, Mark J. Powers, Aaron D. Dyer, Philip J. Currie   +3 more
wiley   +1 more source

The Effect of Maternal Haemoglobinopathies and Iron Deficiency Anaemia on Foetal Growth Restriction: A Systematic Review and Meta‐Analysis

Maternal &Child Nutrition, EarlyView.
This meta‐analysis demonstrates a significant association between maternal anaemia and a 30% increased risk of intrauterine growth restriction (IUGR). These findings emphasize the need for early identification and effective management of anaemia during pregnancy to improve foetal outcomes.
Rajeev Jayalakshmi, Shilpa Gaidhane, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M. Ravi Kumar, Sarvesh Rustagi, Mahalaqua Nazli Khatib, Nishant Rai, Sanjit Sah, Sorabh Lakhanpal, Hashem Abu Serhan, Ganesh Bushi, Muhammed Shabil   +14 more
wiley   +1 more source

Vesiculation as potential novel pathogenic mechanism in autoimmune hemolytic anemia

Transfusion, EarlyView.
Abstract Background Autoimmune hemolytic anemia (AIHA) is typically mediated by immunoglobulin G (IgG) or immunoglobulin M (IgM) antibodies, and more rarely by immunoglobulin A (IgA). The mechanism of red blood cell (RBC) destruction in IgA‐mediated AIHA is not well understood.
Esther C. W. de Boer, Femke V. M. Mulder, Silvia Neri, Marije Wiskerke ‐ van Stuijvenberg, Janine J. G. Arts, Simon Tol, Boukje Beuger, Matthieu C. J. Bosman, Noortje Thielen, René van der Griend, Claudia C. Folman, Masja de Haas, Robin van Bruggen, Richard B. Pouw, Josephine M. I. Vos   +14 more
wiley   +1 more source

Contemporary use and safety of prepartum autologous blood donation: A retrospective cohort study in Quebec, Canada

Transfusion, EarlyView.
Abstract Background Autologous blood donation (ABD) can be indicated in pregnant individuals with rare blood groups. Yet, unlike hospitals, some blood establishments are reluctant to collect ABDs in this population. Therefore, we evaluated the safety and use of prepartum ABD conducted by a blood establishment.
Catherine Dubé, Catherine Latour, Jessica Constanzo Yanez, Nancy Robitaille   +3 more
wiley   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Barriers to Hematopoietic Stem Cell Transplant Among Caregivers and Adolescents With Sickle Cell Disease

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) is a curative treatment for sickle cell disease (SCD). However, barriers exist that prevent access to this treatment modality. Methods An IRB‐approved mixed‐method survey of barriers to HSCT in SCD was given to parents, caregivers, and adolescents obtaining care at the Children's of ...
Chibuzo Ilonze, Alexandria Broadnax, Hilary Haines, Jeffrey Lebensburger, Frederick Goldman   +4 more
wiley   +1 more source

Sickle Cell Story Club: Implementation of a Clinic‐Based Literacy Promotion Program

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Literacy promotion is central to child development, particularly for children with sickle cell disease (SCD) given patterns of neurocognitive involvement. Book ownership programs offer a unique strategy within pediatric healthcare. This study aimed to evaluate the implementation of a literacy promotion program within an outpatient ...
Julia E. LaMotte, Jillian R. Bouck, Kristen Pogue, Lauren Fancher, Olivia Coughlin, Seethal A. Jacob   +5 more
wiley   +1 more source

Cost‐effectiveness of interventions for screening and management of sickle cell disease during pregnancy: A systematic review

Pregnancy, Volume 1, Issue 4, July 2025.
Abstract Background Sickle cell disease (SCD) is a widespread inherited condition that has increased in global prevalence by 41% since 2000. Despite advancements in understanding the pathophysiology and clinical management of SCD, limited evidence exists regarding the economic implications of interventions for managing the disease during pregnancy ...
Jenny Jung, Samia Aziz, Maureen Makama, Nick Scott, Katherine E. Eddy, Joshua F. Ginnane, Joshua P. Vogel   +6 more
wiley   +1 more source

Antenatal medication management for women with sickle‐cell disease: A systematic review

Pregnancy, Volume 1, Issue 4, July 2025.
Abstract Background Improvements in sickle‐cell disease (SCD) treatment have led to an increasing number of individuals surviving to reproductive age. However, pregnancy in women with SCD carries a heightened risk of maternal and fetal complications.
Yaneve N. Fonge, Kelli D. Barbour, Sarah Boudova, Jen Sothornwit, Chetta Ngamjarus, Porjai Pattanittum, Apiwat Jongjakapun, Termtem Waidee, Nampet Jampathong, Pisake Lumbiganon, Beth L. Pineles   +10 more
wiley   +1 more source