Results 91 to 100 of about 1,233,173 (377)

Updates of the HbVar database of human hemoglobin variants and thalassemia mutations

Nucleic Acids Res., 2013
HbVar (http://globin.bx.psu.edu/hbvar) is one of the oldest and most appreciated locus-specific databases launched in 2001 by a multi-center academic effort to provide timely information on the genomic alterations leading to hemoglobin variants and all ...
B. Giardine, Joseph Borg, Emmanouil Viennas, C. Pavlidis, K. Moradkhani, P. Joly, M. Bartsakoulia, C. Riemer, W. Miller, G. Tzimas, H. Wajcman, R. Hardison, G. Patrinos   +12 more
semanticscholar   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Biochemical changes in Salminus brasiliensis due to successive captures and stocking densities - doi: 10.4025/actascibiolsci.v35i1.13055

Acta Scientiarum: Biological Sciences, 2012
This study evaluated the biochemical changes associated to successive captures of Salminus brasiliensis reared at different stocking densities. The experiment was conducted in tanks with a capacity of 1,000 L, connected to a recirculating system with ...
Neiva Braun, Ronaldo Lima de Lima, Bernardo Baldisserotto, Alcir Luiz Dafre, Alex Pires de Oliveira Nuñer   +4 more
doaj   +1 more source

From Unit to Dose: A Machine Learning Approach for Precise Prediction of Hemoglobin and Iron Content in Individual Packed Red Blood Cell Units

Advanced Science, 2022
Transfusion of packed red blood cells (pRBCs) saves lives, but iron overload limits survival of chronically transfused patients. Quality control methods, which involve entering pRBC units and removing them from the blood supply, reveal that hemoglobin ...
Jeremy Epah, Ilay Gülec, Stefan Winter, Johanna Dörr, Christof Geisen, Eva Haecker, Dietmar Link, Matthias Schwab, Erhard Seifried, Richard Schäfer   +9 more
doaj   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

The eff ect of poliodoxin and tilmox 25% on the morphological and biochemical parameters of the blood of broiler chickens

Науковий вісник ветеринарної медицини, 2020
The article presents the results of studies of the eff ect of the drug “Poledoxin”, which belongs to the group of tetracyclines and the drug “Tilmox 25%”, belonging to the group of macrolides, on some morphological and biochemical parameters of blood of ...
Tyshkivskaya A., V. Dukhnitsky, Tyshkivsky M.   +2 more
doaj   +1 more source

The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration?

Blood, 2006
The diagnosis of anemia is an important aspect of the practice of hematology. The first step is to decide whether the patient is, in fact, anemic. Unless earlier blood counts are available, and they often are not, the physician must make his or her ...
E. Beutler, J. Waalen
semanticscholar   +1 more source

Coffee Consumption Is Associated With Later Age‐at‐Onset of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Observation studies suggest that coffee consumption may lower the risk and delay the age‐at‐onset (AAO) of Parkinson's disease (PD). The aim of this study was to explore the causal relationship and genetic association between coffee consumption and the AAO, risk, and progression of PD. Using Mendelian randomization, we identified a significant
Dariia Kuzovenkova, Lang Liu, Ziv Gan‐Or, Konstantin Senkevich   +3 more
wiley   +1 more source

Glycated hemoglobin measurement and prediction of cardiovascular disease.

Journal of the American Medical Association (JAMA), 2014
IMPORTANCE The value of measuring levels of glycated hemoglobin (HbA1c) for the prediction of first cardiovascular events is uncertain. OBJECTIVE To determine whether adding information on HbA1c values to conventional cardiovascular risk factors is ...
E. di Angelantonio, P. Gao, H. Khan, A. Butterworth, D. Wormser, S. Kaptoge, S. R. Kondapally Seshasai, A. Thompson, N. Sarwar, P. Willeit, P. Ridker, E. Barr, K. Khaw, B. Psaty, H. Brenner, B. Balkau, J. Dekker, D. Lawlor, M. Daimon, J. Willeit, I. Njølstad, A. Nissinen, E. Brunner, L. Kuller, J. Price, J. Sundström, M. Knuiman, E. Feskens, W. Verschuren, N. Wald, S. Bakker, P. Whincup, I. Ford, U. Goldbourt, A. Gómez-de-la-Cámara, J. Gallacher, L. Simons, A. Rosengren, S. Sutherland, C. Björkelund, D. Blazer, S. Wassertheil-Smoller, A. Onat, A. Marín Ibañez, E. Casiglia, J. Jukema, Lara M. Simpson, S. Giampaoli, B. Nordestgaard, R. Selmer, P. Wennberg, J. Kauhanen, J. Salonen, R. Dankner, E. Barrett-Connor, M. Kavousi, V. Gudnason, Denis A. Evans, Robert B. Wallace, M. Cushman, R. D’Agostino, J. Umans, Y. Kiyohara, H. Nakagawa, S. Sato, R. Gillum, A. Folsom, Y. T. van der Schouw, K. Moons, S. Griffin, N. Sattar, N. Wareham, E. Selvin, S. Thompson, J. Danesh   +74 more
semanticscholar   +1 more source

Precision‐Optimised Post‐Stroke Prognoses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope, Howard Bowman, Rachel M. Bruce, Alex P. Leff, Cathy J. Price   +4 more
wiley   +1 more source