Results 71 to 80 of about 1,033,134 (305)

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Association of iron status indicators with thyroid hormone concentrations during pregnancy: a systematic review and meta-analysis

Frontiers in Endocrinology
BackgroundMaternal thyroid hormones play a vital role in fetal development, and imbalances can lead to adverse outcomes. Iron deficiency may impair thyroid function due to iron’s essential role in iodine oxidation during thyroid hormone synthesis.
Mohammadamin Parsaei, Mohadese Dashtkoohi, Elahe Amirkhalili, Mohammadreza Chashmyazdan, Tim I. M. Korevaar, Tim I. M. Korevaar, Pantea Nazeri   +6 more
doaj   +1 more source

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Ahlquist, Allison, Allison, Allison, Allison, Atkin, Barrows, Brenner, Burtonwood, Callum G. Fraser, Center, Cole, Cole, Cole, Cole, Crotta, Denters, Digby, Fleisher, Fletcher, Fraser, Fraser, Fraser, Fraser, Fraser, Graeme P. Young, Grazzini, Halloran, Hardcastle, Hewitson, Hoff, Hol, Imperiale, Imperiale, James E. Allison, Jemal, Jemal, Khalid-de Bakker, Kronborg, Levi, Levi, Levin, Mandel, Morikawa, Niv, Osborn, Park, Petrelli, Potter, Potter, Potter, Potter, Potter, Qaseem, Quintero, Raginel, Robinson, Rozen, Saito, Saito, Schoen, Segnan, Segnan, Shaukat, Shimbo, Simon, Songster, Songster, St John, Steele, Steele, Stegeman, Stephen P. Halloran, Sugerman, Tao, van Roon, van Roon, van Roon, van Rossum, Vart, Vellacott, Ventura, Walsh, Williams, Young, Zajac, Zauber   +86 more
core   +3 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Impact of Hemoglobin, Leucocyte and Thrombocyte Levels at Diagnosis on the Survival Outcomes of Chronic Myeloid Leukemia Patients

Genel Tıp Dergisi
Background:Since the development of tyrosine kinase inhibitors (TKIs), the prognosis for chronic myeloid leukemia (CML) has significantly improved. Several predicted prognostic scores and indicators at diagnosis have been used to predict the prognosis of
Taha Ulutan Kars, Atakan Tekinalp, Rafiye Ciftciler, Sinan Demircioğlu   +3 more
doaj   +1 more source

Effects of the Zanzibar School-Based Deworming Program on Iron Status of Children. [PDF]

, 1998
We evaluated the effects of the Zanzibar school-based deworming program on the iron status of primary school children. Parasitologic and nutritional assessments were carried out at baseline, 6 mo, and 12 mo in 4 nonprogram schools (n = 1002), 4 schools ...
Albonico, M, Chwaya, H M, Savioli, L, Schulze, K J, Stoltzfus, R J, Tielsch, J M   +5 more
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

The Multifunctional Catalytic Hemoglobin from Amphitrite ornata: Protocols on Isolation, Taxonomic Identification, Protein Extraction, Purification, and Characterization

Methods and Protocols
The multifunctional catalytic hemoglobin from the terebellid polychaete Amphitrite ornata, also named dehaloperoxidase (AoDHP), utilizes the typical oxygen transport function in addition to four observed activities involved in substrate oxidation.
Anna L. Husted, Victoria R. Sutton, Lauren A. Presnar, R. Kevin Blackburn, Joseph L. Staton, Stephen A. Borgianini, Edward L. D’Antonio   +6 more
doaj   +1 more source

The effect of topical application of tranexamic acid on the occurrence of postoperative hematoma after inguinal hernia repair using the Lichtenstein technique [PDF]

Srpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. The objective of the study was to determine whether the local application of tranexamic acid (TXA) by pouring over the surgical wound reduces the incidence of postoperative hematoma and the occurrence of postoperative bleeding in ...
Kunkin Vanja, Zeljković Vesna
doaj   +1 more source

The Virginia Sickle Cell Anemia Awareness Program: Education, Screening, and Counseling [PDF]

, 1977
In 1968, a program of screening for sickle trait carriers was begun as part of the work of the Hematology Division, Department of Medicine, at the Medical College of Virginia.
Cooper, Florence N., Scott, Robert B.
core   +1 more source