Results 61 to 70 of about 827,803 (310)

Fiber depolymerization [PDF]

, 2006
Depolymerization is, by definition, a crucial process in the reversible assembly of various biopolymers. It may also be an important factor in the pathology of sickle cell disease.
Turner, Matthew S., Ferrone, F.A., Agarwal, G., Wang, J.C., Jones, C. W., Kwong, S., Briehl, R. W., Briehl, R.W., Wang, J. C., Ferrone, F. A., Josephs, R., Jones, C.W., Turner, M.S.   +12 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Successful Treatment of a Child with Hemoglobin Hammersmith with Hematopoietic Stem Cell Transplantation

, 2023
Hemoglobin (Hb) Hammersmith, formed by serine substitution for phenylalanine at residue 42 in the beta-globin chain, is a very rare variant of unstable hemoglobin with low oxygen affinity. For patients with hemoglobinopathies, it is well-established that
Özek, Gülcihan, Gülcihan Özek, Türedi Yıldırım, Ayşen, Türkmen, Hulya, Durmaz, Burak, Gülen, Hüseyin, Hülya Türkmen, Ayşen Türedi Yıldırım, Oymak, Yeşim, Burak Durmaz, Yeşim Oymak, Karaca, Emin, Emin Karaca, Hüseyin Gülen   +13 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Comparative Study of Blood Hemoglobin between Calculated Method through ABG Analyzer and Impedance Method through Fully Automated Blood Cell Counter [PDF]

Indian Journal of Medical Biochemistry
Background: In routine clinical laboratory practice, hemoglobin estimation is done through an automated blood cell counter, which is a fast, inexpensive and convenient method of estimation.
Arvi V Mehta, Sapna P Patel, Hina B Baraiya, Piyush B Tailor   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Lead (Pb) Exposure on Hemoglobin Levels and Decreasing Lung Function of Fuel Station Workers Banjarmasin

The Indonesian Journal of Occupational Safety and Health
Introdution:Exposure to airborne pollutants such as lead (Pb) can cause health problems. Fuel stations are one of the places with a high risk of Pb exposure sourced from fuel or motor vehicle exhaust emissions.
Muhamad Taufiqurrahman, Isa Ansori, Meitria Syahadatina Noor, Haryati Haryati, Ali Assagaf, Mohamad Isa   +5 more
doaj   +1 more source

MOLECULAR LESION FREQUENCY OF HEMOGLOBIN GENE DISORDERS IN TAIWAN

, 2012
[[abstract]]Hemoglobin (Hb) gene disorders are common inherited diseases in Taiwan. The αα- and ββ-thalassemias are among the well-known Hb diseases in this area. We reviewed abnormal hematological data in 3578 cases, identified between 1998 and 2009, as
彭慶添
core  

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source